Pelagiomicin B
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-02377 |
| CAS | 173485-81-9 |
| Molecular Weight | 383.40 |
| Molecular Formula | C20H21N3O5 |
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Description
It is produced by the strain of Pelagiobacter variabilis.
Specification
| Synonyms | Antibiotic 2088B; L-Valine, (6-carboxy-4-methoxy-1-phenazinyl)methyl ester |
| IUPAC Name | 6-[[(2S)-2-amino-3-methylbutanoyl]oxymethyl]-9-methoxyphenazine-1-carboxylic acid |
| Canonical SMILES | CC(C)C(C(=O)OCC1=CC=C(C2=NC3=C(C=CC=C3N=C12)C(=O)O)OC)N |
| InChI | InChI=1S/C20H21N3O5/c1-10(2)15(21)20(26)28-9-11-7-8-14(27-3)18-16(11)22-13-6-4-5-12(19(24)25)17(13)23-18/h4-8,10,15H,9,21H2,1-3H3,(H,24,25)/t15-/m0/s1 |
| InChI Key | PIEWZDRTLBDIHP-HNNXBMFYSA-N |
Properties
| Appearance | Redorange Needles |
| Solubility | Soluble in Chloroform, Methanol, Butanol |
Reference Reading
1. New anticancer antibiotics pelagiomicins, produced by a new marine bacterium Pelagiobacter variabilis
N Imamura, M Nishijima, T Takadera, K Adachi, M Sakai, H Sano J Antibiot (Tokyo). 1997 Jan;50(1):8-12. doi: 10.7164/antibiotics.50.8.
In the course of our screening for new anticancer compounds produced by marine bacteria, we found that a new genus marine bacterium Pelagiobacter variabilis produced new phenazine antibiotics, pelagiomicins A, B and C. Those compounds were labile in water and alcohols. The absolute structure of the main component, pelagiomicin A, and the structures of the minor ones were determined from the spectroscopic data and by synthesis. Pelagiomicin A exhibits activity against Gram-positive and -negative bacteria and antitumor activity in vitro and in vivo.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
