Pentenocin B
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Enzyme inhibitors |
| Catalog number | BBF-02381 |
| CAS | 249283-63-4 |
| Molecular Weight | 158.15 |
| Molecular Formula | C7H10O4 |
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Description
It is produced by the strain of Trichoderma hamatum FO-6903. It weakly inhibits the activity of interleukin-1 and β-transferase (ICE) with IC50 (μmol/L) of 575 and 250, respectively.
Specification
| Synonyms | (+)-Pentenocin B; 2-Cyclopenten-1-one, 4,5-dihydroxy-4-[(1R)-1-hydroxyethyl]-, (4S,5R)- |
| IUPAC Name | (4S,5R)-4,5-dihydroxy-4-[(1R)-1-hydroxyethyl]cyclopent-2-en-1-one |
| Canonical SMILES | CC(C1(C=CC(=O)C1O)O)O |
| InChI | InChI=1S/C7H10O4/c1-4(8)7(11)3-2-5(9)6(7)10/h2-4,6,8,10-11H,1H3/t4-,6+,7+/m1/s1 |
| InChI Key | NEVXRVUNMDEPDG-PIYBLCFFSA-N |
Properties
| Appearance | Light Brown Resinous Solid |
| Solubility | Soluble in Water |
Reference Reading
1. Total synthesis and absolute stereochemistry of pentenocin B, a novel interleukin-1 beta converting enzyme inhibitor
Tsutomu Sugahara, Hayato Fukuda, Yoshiharu Iwabuchi J Org Chem. 2004 Mar 5;69(5):1744-7. doi: 10.1021/jo035430x.
Four possible diastereomers of pentenocin B were synthesized in a stereocontrolled manner, and the first total synthesis of a natural enantiomer of (+)-pentenocin B unequivocally established the absolute stereochemistry to be 4S,5R,6R.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
