Pestalasin A

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Pestalasin A
Category Others
Catalog number BBF-04914
CAS 1193680-49-7
Molecular Weight 264.27
Molecular Formula C14H16O5

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Description

Pestalasin A is a bioactive metabolite from Penicillium purpurogenum.

Specification

IUPAC Name 3-(2-hydroxypropyl)-6,8-dimethoxychromen-2-one
Canonical SMILES CC(CC1=CC2=CC(=CC(=C2OC1=O)OC)OC)O
InChI InChI=1S/C14H16O5/c1-8(15)4-10-5-9-6-11(17-2)7-12(18-3)13(9)19-14(10)16/h5-8,15H,4H2,1-3H3
InChI Key PLDKULNDBSIKSW-UHFFFAOYSA-N

Reference Reading

1. Enhancement of metabolites productivity of Penicillium pinophilum FKI-5653, by co-culture with Trichoderma harzianum FKI-5655
Kenichi Nonaka, Tadahide Abe, Masato Iwatsuki, Mihoko Mori, Tsuyoshi Yamamoto, Kazuro Shiomi, Satoshi Omura, Rokuro Masuma J Antibiot (Tokyo). 2011 Dec;64(12):769-74. doi: 10.1038/ja.2011.91. Epub 2011 Oct 19.
In the course of discovering new metabolites from co-culture of Penicillium pinophilum FKI-5653 and Trichoderma harzianum FKI-5655, a new compound, designated secopenicillide C, and four known compounds, penicillide, MC-141, pestalasin A and stromemycin were isolated. The production of these compounds, except pestalasin A, was enhanced in co-culture to be two to six times higher than in pure culture of Penicillium pinophilum FKI-5653, which was the producer of these compounds.

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