Phenazostatin B
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| Category | Others |
| Catalog number | BBF-02387 |
| CAS | |
| Molecular Weight | 530.57 |
| Molecular Formula | C32H26N4O4 |
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Description
It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.33 μg/mL.
Specification
| IUPAC Name | methyl 6-[3-(6-methoxycarbonylphenazin-1-yl)butan-2-yl]phenazine-1-carboxylate |
| Canonical SMILES | CC(C1=C2C(=CC=C1)N=C3C(=N2)C=CC=C3C(=O)OC)C(C)C4=C5C(=CC=C4)N=C6C(=N5)C=CC=C6C(=O)OC |
| InChI | InChI=1S/C32H26N4O4/c1-17(19-9-5-13-23-27(19)33-25-15-7-11-21(29(25)35-23)31(37)39-3)18(2)20-10-6-14-24-28(20)34-26-16-8-12-22(30(26)36-24)32(38)40-4/h5-18H,1-4H3 |
| InChI Key | WAOUDSYSWNZZKK-UHFFFAOYSA-N |
Properties
| Appearance | Yellow Crystal |
| Solubility | Soluble in Chloroform, Methanol |
Reference Reading
1. New diphenazines with neuronal cell protecting activity, phenazostatins A and B, produced by Streptomyces sp
W G Kim, I J Ryoo, B S Yun, K Shin-ya, H Seto, I D Yoo J Antibiot (Tokyo). 1997 Sep;50(9):715-21. doi: 10.7164/antibiotics.50.715.
Phenazostatins A and B, new diphenazine compounds, were isolated from the culture broth of Streptomyces sp. 833 as new neuronal cell protecting substances which also showed free radical scavenging activity. In the cell assay, phenazostatins A and B inhibited glutamate toxicity in N18-RE-105 cells with EC50 values of 0.34 and 0.33 microM, respectively.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
