Phosmidosine C
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Others |
| Catalog number | BBF-02414 |
| CAS | |
| Molecular Weight | 376.26 |
| Molecular Formula | C11H17N6O7P |
Online Inquiry
Description
It is produced by the strain of Str. sp. RK-16.
Specification
| IUPAC Name | 6-amino-9-[(2R,3R,4S,5R)-5-[[amino(methoxy)phosphoryl]oxymethyl]-3,4-dihydroxyoxolan-2-yl]-7H-purin-8-one |
| Canonical SMILES | COP(=O)(N)OCC1C(C(C(O1)N2C3=NC=NC(=C3NC2=O)N)O)O |
| InChI | InChI=1S/C11H17N6O7P/c1-22-25(13,21)23-2-4-6(18)7(19)10(24-4)17-9-5(16-11(17)20)8(12)14-3-15-9/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,21)(H,16,20)(H2,12,14,15)/t4-,6-,7-,10-,25?/m1/s1 |
| InChI Key | RENSJGNFTDPDED-ACFLSSRZSA-N |
Properties
| Melting Point | 230°C (dec.) |
| Solubility | Soluble in Water |
Reference Reading
1. Morphology reversion activity of phosmidosine and phosmidosine B, a newly isolated derivative, on src transformed NRK cells
N Matsuura, R Onose, H Osada J Antibiot (Tokyo). 1996 Apr;49(4):361-5. doi: 10.7164/antibiotics.49.361.
An antifungal antibiotic, phosmidosine (1) was previously isolated (J. Antibiotics 44: 375 approximately 381, 1991). Phosmidosine derivatives, phosmidosines B (2) and C (3) were newly isolated as detransforming compounds from the fermentation broth of Streptomyces sp. strain RK-16 which is a producer strain of phosmidosine (1). The structures of 2 and 3 were established by spectroscopic methods, including UV, HRFAB-MS, and NMR. 1 and 2 showed the inhibitory activity of the cell cycle progression and the morphological reversion activity on srcts-NRK cells. On the other hand, 3 had no activity. These results indicate that the prolyl group in phosmidosine derivatives plays an important role in the inhibitory activity against the cell cycle progression and the morphological reversion activity on srcts-NRK cells.
Recommended Products
| BBF-04061 | Allocholic acid | Inquiry |
| BBF-02575 | Pneumocandin A0 | Inquiry |
| BBF-01851 | Fumagillin | Inquiry |
| BBF-03827 | Polymyxin B sulphate | Inquiry |
| BBF-01829 | Deoxynojirimycin | Inquiry |
| BBF-00569 | Aspoxicillin | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
