Pintulin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-02420 |
| CAS | |
| Molecular Weight | 260.24 |
| Molecular Formula | C14H12O5 |
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Description
It is produced by the strain of Penicillium vulpinum F-4148. In in vitro test, it can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50 (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. It has only very weak antibacterial activity against the microorganisms tested.
Specification
| IUPAC Name | 6-[(3-hydroxyphenyl)methoxy]-4,6-dihydrofuro[3,2-c]pyran-2-one |
| Canonical SMILES | C1C2=CC(=O)OC2=CC(O1)OCC3=CC(=CC=C3)O |
| InChI | InChI=1S/C14H12O5/c15-11-3-1-2-9(4-11)7-17-14-6-12-10(8-18-14)5-13(16)19-12/h1-6,14-15H,7-8H2 |
| InChI Key | ZDTFYABNHWHUNO-UHFFFAOYSA-N |
Properties
| Appearance | Colorless Oily Matter |
| Antibiotic Activity Spectrum | Neoplastics (Tumor) |
| Solubility | Soluble in Chloroform, Methanol |
Reference Reading
1. A new isopatulin derivative pintulin produced by Penicillium vulpinum F-4148 taxonomy, isolation, physico-chemical properties, structure and biological properties
A Mikami, T Okazaki, N Sakai, T Ichihara, K Hanada, K Mizoue J Antibiot (Tokyo). 1996 Oct;49(10):985-9. doi: 10.7164/antibiotics.49.985.
During our screening program of natural products from fungal metabolites for drugs effective against tumor cell lines, we discovered a new isopatulin derivative, pintulin, from the fermentation broth of Penicillium vulpinum F-4148. Pintulin shows weak activity against tumor cell lines, compared to that of adriamycin.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
