Pluraflavin C
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| Category | Antibiotics |
| Catalog number | BBF-02036 |
| CAS | |
| Molecular Weight | 840.91 |
| Molecular Formula | C43H56N2O15 |
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Description
Pluraflavin C is an antitumor antibiotic produced by Saccharothrix sp. DSM 12931. It has good anti-proliferation activity on tumor cells.
Properties
| Appearance | Dark Orange Solid |
| Antibiotic Activity Spectrum | neoplastics (Tumor) |
Reference Reading
1. Studies toward the total synthesis of pluraflavin A
John Hartung, Benjamin J D Wright, Samuel J Danishefsky Chemistry. 2014 Jul 7;20(28):8731-6. doi: 10.1002/chem.201402254. Epub 2014 Jun 12.
A synthetic strategy towards the potent cytostatic agent pluraflavin A has been developed. Formation of the enantioenriched anthrapyran core bearing a halogen atom enabled the introduction of the α C-aryl glycoside by Stille cross-coupling and subsequent hydrogenation of the aryl glycal. Chemo- and stereoselective O-glycosylations of α oliose and β 3-epi vancosamine residues afforded a fully glycosylated aromatic core. Attempts to install the dimethylamino group of the C-disaccharide suggest that introduction of an azide group by displacement and subsequent reduction may pave the way to the total synthesis of pluraflavin A.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
