Pretomaymycin
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| Category | Antibiotics |
| Catalog number | BBF-02068 |
| CAS | 28797-41-3 |
| Molecular Weight | 272.30 |
| Molecular Formula | C15H16N2O3 |
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Description
Pretomaymycin is an antibiotic produced by Str. umbrosus subsp. raffinophilus DO-62. It is active against Gram-positive and Gram-negative bacteria and experimental murine tumor sarcoma 180 and leukemia P388.
Specification
| IUPAC Name | (8Z)-8-ethylidene-3-hydroxy-2-methoxy-7,9-dihydro-6aH-pyrrolo[2,1-c][1,4]benzodiazepin-11-one |
| Canonical SMILES | CC=C1CC2C=NC3=CC(=C(C=C3C(=O)N2C1)OC)O |
| InChI | InChI=1S/C15H16N2O3/c1-3-9-4-10-7-16-12-6-13(18)14(20-2)5-11(12)15(19)17(10)8-9/h3,5-7,10,18H,4,8H2,1-2H3/b9-3- |
| InChI Key | MQCBKXNWUKLOOH-OQFOIZHKSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria; neoplastics (Tumor) |
| Boiling Point | 530.5±50.0°C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
Reference Reading
1. Studies on tomaymycin. II. Total syntheses of the antitumor antibiotics, E-and Z-tomaymycins
Z Tozuka, H Takasugi, T Takaya J Antibiot (Tokyo). 1983 Mar;36(3):276-82. doi: 10.7164/antibiotics.36.276.
The total syntheses of naturally occurring E-tomaymycin (1E) and its olefinic geometrical isomer, Z-tomaymycin (1Z) are described. The Z-isomer was found to have the same anti-bacterial activity as E-isomer (1E).
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
