Primocarcin

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Primocarcin
Category Antibiotics
Catalog number BBF-02059
CAS 3750-26-3
Molecular Weight 184.19
Molecular Formula C8H12N2O3

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Description

Primocarcin is an antibiotic produced by Nocardia fukayea 11-41. Antibacterial effect is weak; inoculated with Ehrlich ascites cancer mice intraperitoneally given 0.125-0. 5mg/mouse/day, ascites does not increase, and survival time is more than doubled. For Sarcoma-180, given the same dose, the same effect was achieved.

Specification

Synonyms 5-(Acetylamino)-4-oxo-5-hexenamide; 4-Acetamido-4-penten-3-one-1-carboxamide
IUPAC Name 5-acetamido-4-oxohex-5-enamide
Canonical SMILES CC(=O)NC(=C)C(=O)CCC(=O)N
InChI InChI=1S/C8H12N2O3/c1-5(10-6(2)11)7(12)3-4-8(9)13/h1,3-4H2,2H3,(H2,9,13)(H,10,11)
InChI Key DVMKENULKFKEFR-UHFFFAOYSA-N

Properties

Appearance Colorless Needle Crystal
Antibiotic Activity Spectrum neoplastics (Tumor)
Boiling Point 544.5°C at 760 mmHg
Melting Point 130-131°C
Density 1.155 g/cm3

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