Propineb
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Others |
| Catalog number | BBF-03805 |
| CAS | 12071-83-9 |
| Molecular Weight | 289.78 |
| Molecular Formula | C5H8N2S4Zn |
| Purity | >98% |
Online Inquiry
Description
Propineb is an agricultural broad-spectrum fungicide protectant from the dithiocarbamate group of compounds.
Specification
| Synonyms | Methylzineb; Antracol; Mezineb |
| Shelf Life | Limited shelf life, expiry date on the label |
| Storage | Store at -20°C |
| IUPAC Name | zinc;N-[1-(sulfidocarbothioylamino)propan-2-yl]carbamodithioate |
| Canonical SMILES | CC(CNC(=S)[S-])NC(=S)[S-].[Zn+2] |
| InChI | InChI=1S/C5H10N2S4.Zn/c1-3(7-5(10)11)2-6-4(8)9;/h3H,2H2,1H3,(H2,6,8,9)(H2,7,10,11);/q;+2/p-2 |
| InChI Key | KKMLIVYBGSAJPM-UHFFFAOYSA-L |
Properties
| Appearance | White to Pale Yellow Solid |
| Boiling Point | 315.4°C at 760 mmHg |
| Melting Point | 160°C |
| Solubility | Soluble in DMSO |
Toxicity
| Toxicity | An agent that can induce an allergic reaction in the skin. |
Reference Reading
1. Analytical method validation, dissipation and safety evaluation of combination fungicides fenamidone + mancozeb and iprovalicarb + propineb in/on tomato
Sujoy Saha, Kaushik Banerjee, Manjusha Jadhav, Awadhesh Bahadur Rai, Sandip Hingmire, Yengkhom Bijen Kumar, T P Ahammed Shabeer J Food Sci Technol . 2020 Jun;57(6):2061-2069. doi: 10.1007/s13197-020-04240-9.
Dissipation behavior and degradation kinetics of fenamidone + mancozeb (Sectin 60 WG) and iprovalicarb + propineb (Melody Duo 66.75 WP) in tomato were studied at recommended dose (RD) and double dose (DD) of application. The analysis of the field samples were carried out by employing liquid chromatography tandem mass spectrometry (LC-MS/MS) for fenamidone and iprovalicarb residues and gas chromatography mass spectrometry for mancozeb and propineb residues after thorough validation of the extraction methods. The dissipation of residues best followed 1st + 1st order for all the test fungicides. The half-life period for fenamidone, mancozeb, iprovalicarb and propineb were 2, 2, 1.5 and 2 days for RD and 3, 2.5, 2 and 3 days for DD, respectively. The pre-harvest intervals were not applicable for iprovalicarb, fenamidone and mancozeb (at RD) as the residues at 0 day were below maximum residue limit set by European Union, and it was 1 day for DD of iprovalicarb, 3.5 days for DD of fenamidone, 3 days for DD of mancozeb, 3 and 7 days for propineb at RD and DD, respectively. A PHI of 4 and 7 days are proposed for fenamidone + Mancozeb and iprovalicarb + propineb, respectively. Dietary exposure calculated for all the pesticides were safe on all the sampling days except for propineb residues for which it was safe after first day of the double dose application. The study will be useful for promoting effective residue management and safe use of these chemicals for controlling fungal diseases in tomato crop.
2. Determination of propineb and its metabolites propylenethiourea and propylenediamine in banana and soil using gas chromatography with flame photometric detection and LC-MS/MS analysis
Zhaojie Chen, Xuesheng Li, Shiming Song, Yuhao Lei, Yan Zhang, Jie Wei, Cheng Deng, Huihua Tan J Environ Sci Health B . 2018 Mar 4;53(3):153-160. doi: 10.1080/03601234.2017.1399765.
A sensitive and specific method for the determination of propineb and its metabolites, propylenethiourea (PTU) and propylenediamine (PDA), using gas chromatography with flame photometric detection (GC-FPD) and LC-MS/MS was developed and validated. Propineb and its metabolite residue dynamics in supervised field trials under Good Agricultural Practice (GAP) conditions in banana and soil were studied. Recovery of propineb (as CS2), PDA and PTU ranged from 75.3 to 115.4% with RSD (n = 5) of 1.3-11.1%. The limit of quantification (LOQ) of CS2, PDA and PTU ranged from 0.005 to 0.01 mg kg-1, and the limit of detection (LOD) ranged from 0.0015 to 0.0033 mg kg-1. Dissipation experiments showed that the half-life of propineb in banana and soil ranged from 4.4 to 13.3 days. PTU was found in banana with a half-life of 31.5-69.3 days, while levels of PDA were less than 0.01 mg kg-1in banana and soil. It has been suggested that PTU is the major metabolite of propineb in banana. The method was demonstrated to be reliable and sensitive for the routine monitoring of propineb and its metabolites in banana and soil. It also serves as a reference for the detection and monitoring of dithiocarbamates (DTCs) residues and the evaluation of their metabolic pathway.
3. [Determination of thiram, propineb and metiram in mushroom by gas chromatography-mass spectrometry]
Junlin Wang, Zhunan Ni, Zengxuan Cai, Liang Feng, Jing Zhang, Ying Tan Wei Sheng Yan Jiu . 2020 Mar;49(2):267-271. doi: 10.19813/j.cnki.weishengyanjiu.2020.02.017.
Objective:To establish a method for determination of thiram, propineb and metiram in mushroom samples by gas chromatography-mass spectrometry(GC-MS).Methods:Insoluble heavy metal salts were converted into water-soluble sodium salts by alkaline buffer with strong chelating agents. Dithiocarbamates can be converted into different methyl ester compounds with ion pair methylation. The GC separation was performed on a DB-5 MS capillary column(30 m×0. 25 mm, 0. 25 μm). The pesticides were detected by GC-MS with selective ion monitoring(SIM) and quantified by external standard of working curve method. Methodsological verification was carried out based on optimized sample pretreatment and GC-MS condition.Results:The concentrations of dithiocarbamates exhibited a good linear relationship with GC-MS within a certain range. The limits of detection of thiram, propineb and metiram were 0. 01, 0. 05 and 0. 05 mg/kg, respectively. Furthermore, the average recoveries were from 76. 98% to 93. 52%, and the maximum relative standard deviation was 11. 54%(n=6).Conclusion:This method is simple, sensitive, accurate and reliable. All the indices meet the requirements of pesticide residue detection.
Recommended Products
| BBF-00677 | 3-Amino-3-deoxy-D-glucose | Inquiry |
| BBF-01693 | Doxorubicin EP Impurity A (Daunorubicin) | Inquiry |
| BBF-00764 | Cerebroside C | Inquiry |
| BBF-03755 | Actinomycin D | Inquiry |
| BBF-01829 | Deoxynojirimycin | Inquiry |
| BBF-02614 | Nystatin | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
