Rhizonic acid
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| Category | Others |
| Catalog number | BBF-05402 |
| CAS | 479-26-5 |
| Molecular Weight | 196.20 |
| Molecular Formula | C10H12O4 |
| Purity | ≥97% |
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Specification
| Synonyms | Benzoic acid, 2-hydroxy-4-methoxy-3,6-dimethyl-; Rhizoninsaure; 6-Oxy-4-methoxy-2,5-dimethyl-benzoesaeure |
| IUPAC Name | 2-hydroxy-4-methoxy-3,6-dimethylbenzoic acid |
| Canonical SMILES | CC1=CC(=C(C(=C1C(=O)O)O)C)OC |
| InChI | InChI=1S/C10H12O4/c1-5-4-7(14-3)6(2)9(11)8(5)10(12)13/h4,11H,1-3H3,(H,12,13) |
| InChI Key | BMRVNZZVDSVOQG-UHFFFAOYSA-N |
Properties
| Boiling Point | 337.8°C at 760 mmHg |
| Density | 1.25 g/cm3 |
Reference Reading
1. A New Depsidone from Teloschistes flavicans and the Antileukemic Activity
Angga Sanjaya, Avidlyandi Avidlyandi, Morina Adfa, Masayuki Ninomiya, Mamoru Koketsu J Oleo Sci. 2020 Dec 1;69(12):1591-1595. doi: 10.5650/jos.ess20209. Epub 2020 Nov 12.
Lichens produce a variety of secondary metabolites that could be potential sources of pharmaceutically useful chemicals. However, only a limited number of lichen metabolites have been investigated for their biological significance. The objective of this study was to identify the potential compounds responsible for the antileukemic activity of lichen Teloschistes flavicans. Among three fractions (n-hexane, EtOAc, and MeOH-H2O), the ethyl acetate (EtOAc) fraction of T. flavicans methanolic extract showed the strongest inhibition in the HL-60 cell line. Additionally, the EtOAc fraction was further purified to obtain a new depsidone, 2,7-dichloro-3,8-dimethoxy-1,6,9-trimethyl-11H-dibenzo[b,e][1,4]dioxepin-11-one, named as flavicansone, along with rhizonic acid, parietin, and vicanicin. Flavicansone demonstrated the most significant inhibitory action against cell proliferation among the four isolated compounds.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
