Metabolites-BOC Sciences


Catalog number: BBF-03392

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Catalog Number BBF-03392
Description S14-95 is an inhibitor of the JAK/STAT pathway isolated from Penicillium sp. 14-95. It inhibits the IFN-gamma mediated expression of the reporter gene with IC50 values of 2.5 to approximately 5 mg/ml. It inhibits the expression of the proinflammatory enzymes COX-2 and NOS II at 5 microg/ml (10.8 mM) in LPS/IFN-gamma stimulated J774 mouse macrophages.
Molecular Formula C28H34O5
Molecular Weight 450.57
Appearance Colorless Oily Matter
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