Saframycin F
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Antibiotics |
Catalog number | BBF-02845 |
CAS | 92569-03-4 |
Molecular Weight | 578.57 |
Molecular Formula | C29H30N4O9 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
It is produced by the strain of Str. lavendulae No 314. It has the effect of anti-Gram-positive bacteria, and Saframycin A has the strongest antibacterial activity. It has the effect of inhibiting mouse lymphocyte L-1210 with ID50 of 0.59 μmol/L.
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- Properties
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Synonyms | 21-Cyanosaframycin D; N-[[(6R)-7α-Cyano-6,7,9,10,13,14,14aα,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6α,15α-epimino-5H-isoquino[3,2-b][3]benzazocin-9β-yl]methyl]-2-oxopropionamide; Propanamide, N-[[(6R,7R,9R,14aS,15R)-7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-2-oxo-; Propanamide, N-[(7-cyano-6,7,9,10,13,14,14a,15-octahydro-1,4-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-5,10,13-trioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]-2-oxo-, [6R-(6a,7a,9b,14aa,15a)]-; (+)-Saframycin F |
IUPAC Name | N-[[(1R,2S,10R,12R,13R)-12-cyano-16,19-dihydroxy-7,18-dimethoxy-6,17,21-trimethyl-5,8,14-trioxo-11,21-diazapentacyclo[11.7.1.02,11.04,9.015,20]henicosa-4(9),6,15(20),16,18-pentaen-10-yl]methyl]-2-oxopropanamide |
Canonical SMILES | CC1=C(C2=C(C3C4CC5=C(C(N4C(C(C2=O)N3C)C#N)CNC(=O)C(=O)C)C(=O)C(=C(C5=O)C)OC)C(=C1OC)O)O |
InChI | InChI=1S/C29H30N4O9/c1-10-22(35)13-7-14-20-18-19(23(36)11(2)28(42-6)26(18)39)24(37)21(32(20)4)15(8-30)33(14)16(9-31-29(40)12(3)34)17(13)25(38)27(10)41-5/h14-16,20-21,36,39H,7,9H2,1-6H3,(H,31,40)/t14-,15-,16-,20-,21+/m0/s1 |
InChI Key | WDQZQIAZHSHOFD-KUVPCWQVSA-N |
Appearance | Pale Yellow Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria; Neoplastics (Tumor) |
Melting Point | 134-136°C (dec.) |
Density | 1.52±0.1 g/cm3 (Predicted) |
Solubility | Soluble in Methanol, Chloroform |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
