Sakyomicin D
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| Category | Antibiotics |
| Catalog number | BBF-02853 |
| CAS | 86413-77-6 |
| Molecular Weight | 374.34 |
| Molecular Formula | C19H18O8 |
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Description
It is a Benzoquinone antibiotic produced by the strain of Nocardia sp. M-53. It has activity against gram-positive bacteria.
Specification
| Synonyms | Benz[a]anthracene-1,7,12(2H)-trione,3,4,4a,5,6,12b-hexahydro-2,3,4a,8,12b-pentahydroxy-3-methyl-, (2S,3R,4aR,12bR)-; Benz[a]anthracene-1,7,12(2H)-trione,3,4,4a,5,6,12b-hexahydro-2,3,4a,8,12b-pentahydroxy-3-methyl-, [2S-(2a,3b,4aa,12ba)]- |
| IUPAC Name | (2S,3R,4aR,12bR)-2,3,4a,8,12b-pentahydroxy-3-methyl-2,4,5,6-tetrahydrobenzo[a]anthracene-1,7,12-trione |
| Canonical SMILES | CC1(CC2(CCC3=C(C2(C(=O)C1O)O)C(=O)C4=C(C3=O)C(=CC=C4)O)O)O |
| InChI | InChI=1S/C19H18O8/c1-17(25)7-18(26)6-5-9-12(19(18,27)16(24)15(17)23)14(22)8-3-2-4-10(20)11(8)13(9)21/h2-4,15,20,23,25-27H,5-7H2,1H3/t15-,17-,18-,19+/m1/s1 |
| InChI Key | UQVQAGIDTKKVTM-OWYHZJEWSA-N |
Properties
| Appearance | Yellow Fine Needle Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Boiling Point | 678.6°C at 760 mmHg |
| Melting Point | 161-163°C |
| Density | 1.71 g/cm3 |
| Solubility | Soluble in Methanol, Benzene |
Reference Reading
1. Sakyomicins A, B, C and D: new quinone-type antibiotics produced by a strain of Nocardia. Taxonomy, production, isolation and biological properties
T Nagasawa, H Fukao, H Irie, H Yamada J Antibiot (Tokyo). 1984 Jul;37(7):693-9. doi: 10.7164/antibiotics.37.693.
Actinomycete strain M-53, a new soil isolate, was found to produce four quinone-type antibiotics. Antibiotic sakyomicin components, A, B, C and D were isolated from the fermentation broth of strain M-53 by XAD-2 column chromatography, silica gel column chromatography and Sephadex LH-20 column chromatography. The components are active against Gram-positive bacteria. Strain M-53 was identified as a strain of genus Nocardia.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
