Sannamycin C
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| Category | Antibiotics |
| Catalog number | BBF-02868 |
| CAS | 73522-71-1 |
| Molecular Weight | 332.44 |
| Molecular Formula | C15H32N4O4 |
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Description
It is an aminoglycoside antibiotic produced by the strain of Str. sannanensis sp. nov. It has weak antibacterial activity against Gram-positive bacteria.
Specification
| Synonyms | 5-Amino-6-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-2,4,5-trideoxy-3-O-methyl-2-(methylamino)-D-epi-inositol; Antibiotic KA-7038VI; KA-7038VI; D-Epi-inositol, 5-amino-6-o-(2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl)-2,4,5-trideoxy-3-o-methyl-2-(methylamino)-; 3-Episannamycin B |
| IUPAC Name | (1R,2R,3S,5R,6S)-3-amino-2-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-5-methoxy-6-(methylamino)cyclohexan-1-ol |
| Canonical SMILES | CNCC1CCC(C(O1)OC2C(CC(C(C2O)NC)OC)N)N |
| InChI | InChI=1S/C15H32N4O4/c1-18-7-8-4-5-9(16)15(22-8)23-14-10(17)6-11(21-3)12(19-2)13(14)20/h8-15,18-20H,4-7,16-17H2,1-3H3/t8-,9+,10-,11+,12+,13+,14+,15+/m0/s1 |
| InChI Key | GKYYNFPFPFRFFN-YPPZSDNLSA-N |
Properties
| Appearance | Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Boiling Point | 480.6°C at 760 mmHg |
| Density | 1.17 g/cm3 |
| Solubility | Soluble in Methanol, Water, Ether, Ethanol |
Reference Reading
1. A new aminoglycoside antibiotic, sannamycin C and its 4-N-glycyl derivative
T Deushi, T Yamaguchi, K Kamiya, A Iwasaki, T Mizoguchi, M Nakayama, I Watanabe, H Itoh, T Mori J Antibiot (Tokyo). 1980 Nov;33(11):1274-80. doi: 10.7164/antibiotics.33.1274.
Streptomyces sannanensis KC-7038 used for the production of sannamycins A and B has also produced another antibiotic sannamycin C, in the culture broth. Physico-chemical characterization revealed that sannamycin C is a new aminoglycoside antibiotic having 6-N-methylpurpurosamine C and 2-deoxy-3-epi-fortamine. Its 4-N-glycyl derivative indicated inhibitory activity against Gram-positive and Gram-negative bacteria containing aminoglycoside resistant strains.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
