SB-315021
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| Category | Enzyme inhibitors |
| Catalog number | BBF-03404 |
| CAS | |
| Molecular Weight | 554.7 |
| Molecular Formula | C28H46N2O9 |
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Description
SB-315021 is an inhibitor of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579.
Specification
| Synonyms | SB 315021; SB315021 |
| IUPAC Name | N-(1,5-dioxo-5a,6,7,8-tetrahydropyrrolo[1,2-c][1,3]oxazepin-3-yl)-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxytetradecanamide |
| Canonical SMILES | CCCCCCCCCCCC(CC(=O)NC1=CC(=O)C2CCCN2C(=O)O1)OC3C(C(C(C(O3)C)O)O)O |
| InChI | InChI=1S/C28H46N2O9/c1-3-4-5-6-7-8-9-10-11-13-19(38-27-26(35)25(34)24(33)18(2)37-27)16-22(32)29-23-17-21(31)20-14-12-15-30(20)28(36)39-23/h17-20,24-27,33-35H,3-16H2,1-2H3,(H,29,32)/t18-,19?,20?,24-,25+,26+,27-/m0/s1 |
| InChI Key | WAHMOFCRXZFEQB-KITPZMISSA-N |
Properties
| Appearance | Off-white Powder |
Reference Reading
1. SB-253514 and analogues: novel inhibitors of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579. II. Physico-chemical properties and structure elucidation
D J Busby, R C Copley, J A Hueso, S A Readshaw, A Rivera J Antibiot (Tokyo). 2000 Jul;53(7):670-6.
A series of novel inhibitors of lipoprotein associated phospholipase A2 were isolated from the culture broths of Pseudomonas fluorescens strain DSM11579. The inhibitors fall into two structurally isomeric classes each of which comprise compounds incorporating glycosylated hydrocarbon chains. The structure elucidation for the major member of each structural class is reported. The crystal structure of a non-glycosylated analogue of the 5,5-series, produced through biotransformation, is also reported.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
