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Sch 484129

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Category Antibiotics
Catalog number BBF-02438
CAS
Molecular Weight 618.8
Molecular Formula C31H54O12

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Capabilities & Facilities

Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains.

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Synonyms Sch-484129
IUPAC Name 11-[6-(acetyloxymethyl)-3-(2-carboxyacetyl)oxy-4,5-dihydroxyoxan-2-yl]oxyicosanoic acid
Canonical SMILES CCCCCCCCCC(CCCCCCCCCC(=O)O)OC1C(C(C(C(O1)COC(=O)C)O)O)OC(=O)CC(=O)O
InChI InChI=1S/C31H54O12/c1-3-4-5-6-8-11-14-17-23(18-15-12-9-7-10-13-16-19-25(33)34)41-31-30(43-27(37)20-26(35)36)29(39)28(38)24(42-31)21-40-22(2)32/h23-24,28-31,38-39H,3-21H2,1-2H3,(H,33,34)(H,35,36)
InChI Key XVDLULKLSKWATQ-UHFFFAOYSA-N
Appearance Oily Matter
Solubility Soluble in methanol, chloroform.
1. Isolation and characterization of two new antifungal antibiotics from a basidiomycete
Min Chu, Ronald Mierzwa, Ling Xu, Ling He, Erik Langsdorf, Martha Beyazova, Joseph Terracciano, Mahesh Patel, Tze-Ming Chan, Vincent Gullo J Antibiot (Tokyo). 2003 Jan;56(1):9-15. doi: 10.7164/antibiotics.56.9.
Two novel antibiotics, Sch 484129 (1) and Sch 484130 (2), were isolated from the fermentation broth of a fungal culture, which was identified as a Basidiomycete. The new antibiotics were obtained by ethyl acetate extraction followed by reversed phase HPLC purification. Structure elucidation of 1 and 2 was accomplished by spectroscopic data analyses. Derivatizations of the major component 1 were performed in order to provide definitive structural information. Both components were identified as glycolipids and displayed antifungal activity against Saccharomyces and Aspergillus strains.

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Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

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Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
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