Seitomycin
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| Category | Antibiotics |
| Catalog number | BBF-02895 |
| CAS | 630391-05-8 |
| Molecular Weight | 354.35 |
| Molecular Formula | C20H18O6 |
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Description
It is an anthraquinone antibiotic produced by the strain of Streptomyces sp. GW 19/1251. It has moderate activity against Gram-positive bacteria such as Staphylococcus aureus and Bacillus subtilis, Gram-negative bacteria such as Escherichia coli and green Streptomyces chlorophyllus.
Specification
| Synonyms | Benz[a]anthracene-7,12-dione, 1,2,3,4-tetrahydro-1,3,11-trihydroxy-8-methoxy-3-methyl- |
| IUPAC Name | 1,3,11-trihydroxy-8-methoxy-3-methyl-2,4-dihydro-1H-benzo[a]anthracene-7,12-dione |
| Canonical SMILES | CC1(CC(C2=C(C1)C=CC3=C2C(=O)C4=C(C=CC(=C4C3=O)OC)O)O)O |
| InChI | InChI=1S/C20H18O6/c1-20(25)7-9-3-4-10-15(14(9)12(22)8-20)19(24)16-11(21)5-6-13(26-2)17(16)18(10)23/h3-6,12,21-22,25H,7-8H2,1-2H3 |
| InChI Key | GEGOZMWTAFXSGR-UHFFFAOYSA-N |
Properties
| Appearance | Orange Solid |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Solubility | Soluble in Methanol |
Reference Reading
1. Seitomycin: isolation, structure elucidation and biological activity of a new angucycline antibiotic from a terrestrial Streptomycete
Mohamed Abdelfattah, Rajendra P Maskey, Ratnakar N Asolkar, Iris Grün-Wollny, Hartmut Laatsch J Antibiot (Tokyo). 2003 Jun;56(6):539-42. doi: 10.7164/antibiotics.56.539.
A new antibiotic, named seitomycin (1c), and the known microbial metabolite tetrangulol methyl ether (2) were found in the ethyl acetate extract of two terrestrial Streptomyces sp. isolates. The structure of the new antibiotic was elucidated by spectroscopic studies and by comparison of the NMR data with the structurally related hatomarubigin C (1a) and SM-196 B (1b). Seitomycin (1c) showed moderate antimicrobial and weak phytotoxic activity, similar to tetrangulol methyl ether (2).
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
