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SF-2330

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Category Antibiotics
Catalog number BBF-02447
CAS 103947-06-4
Molecular Weight 390.3
Molecular Formula C22H14O7

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Fermentation Lab

4 R&D and scale-up labs

2 Preparative purification labs

Fermentation Plant

Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)

Product Description

SF-2330 is a quinone antibiotic produced by Streptomyces sp. SF-2330. It exhibits activity against gram-positive bacteria.

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Synonyms Antibiotic SF-2330; SF 2330; 4H-Anthra(1,2-b)pyran-4,7,12-trione, 2-(2,2'-bioxiran)-2-yl-11-hydroxy-5-methyl-
IUPAC Name 11-hydroxy-5-methyl-2-[2-(oxiran-2-yl)oxiran-2-yl]naphtho[2,3-h]chromene-4,7,12-trione
Canonical SMILES CC1=CC2=C(C3=C1C(=O)C=C(O3)C4(CO4)C5CO5)C(=O)C6=C(C2=O)C=CC=C6O
InChI InChI=1S/C22H14O7/c1-9-5-11-18(20(26)17-10(19(11)25)3-2-4-12(17)23)21-16(9)13(24)6-14(29-21)22(8-28-22)15-7-27-15/h2-6,15,23H,7-8H2,1H3
InChI Key FKRPAYLQUQJMJZ-UHFFFAOYSA-N
Appearance Orange Needle Crystal
Antibiotic Activity Spectrum Gram-positive bacteria
Melting Point 233-235°C (dec.)
1. Studies on a new antibiotic SF-2330. I. Taxonomy, isolation and characterization
J Itoh, T Shomura, T Tsuyuki, J Yoshida, M Ito, M Sezaki, M Kojima J Antibiot (Tokyo). 1986 Jun;39(6):773-9. doi: 10.7164/antibiotics.39.773.
A new antibiotic SF-2330 active against Gram-positive bacteria has been isolated from the culture broth of Streptomyces sp. SF-2330. The antibiotic was obtained as orange needle crystals and its molecular formula was C22H14O7. This is a new member of the pluramycin group antibiotics.
2. Studies on a new antibiotic SF-2330. II. The structural elucidation
J Itoh, T Tsuyuki, K Fujita, M Sezaki J Antibiot (Tokyo). 1986 Jun;39(6):780-3. doi: 10.7164/antibiotics.39.780.
The structure of antibiotic SF-2330 has been elucidated to be 11-hydroxy-5-methyl-2-(2,2'-bioxiran-2-yl)-4H-anthra[1,2-b] pyran-4,7,12-trione by spectral analyses. The olefinic side chain at C-2 of alpha-indomycinone is replaced by a bioxiran-2-yl group in SF-2330.

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