SF2457
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| Category | Antibiotics |
| Catalog number | BBF-02459 |
| CAS | 115748-04-4 |
| Molecular Weight | 590.6 |
| Molecular Formula | C27H38N6O9 |
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Description
SF2457 is an antibiotic related to amicetin, which is isolated from the fermentation broth of Nocardia brasiliensis SF2457. It exhibits inhibitory activity against Gram-positive and Gram-negative bacteria.
Specification
| Synonyms | SF-2457; SF 2457 |
| IUPAC Name | 4-[[(2R)-2-aminopropanoyl]amino]-N-[1-[(2R,4R,5S,6R)-5-[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]-2-oxopyrimidin-4-yl]benzamide |
| Canonical SMILES | CC1C(C(C(C(O1)OC2C(OC(CC2O)N3C=CC(=NC3=O)NC(=O)C4=CC=C(C=C4)NC(=O)C(C)N)C)O)O)NC |
| InChI | InChI=1S/C27H38N6O9/c1-12(28)24(37)30-16-7-5-15(6-8-16)25(38)31-18-9-10-33(27(39)32-18)19-11-17(34)23(14(3)40-19)42-26-22(36)21(35)20(29-4)13(2)41-26/h5-10,12-14,17,19-23,26,29,34-36H,11,28H2,1-4H3,(H,30,37)(H,31,32,38,39)/t12-,13-,14-,17-,19-,20-,21+,22-,23-,26-/m1/s1 |
| InChI Key | MRCNWCHLQHYMMZ-AOHSPZNCSA-N |
Properties
| Appearance | Solid Powder |
| Antibiotic Activity Spectrum | Gram-positive bacteria; Gram-negative bacteria |
| Melting Point | 172-174°C (dec.) |
Reference Reading
1. SF2457, a new antibiotic related to amicetin
J Itoh, S Miyadoh J Antibiot (Tokyo). 1992 Jun;45(6):846-53. doi: 10.7164/antibiotics.45.846.
A novel nucleoside antibiotic, SF2457, was isolated from the fermentation broth of Nocardia brasiliensis SF2457. The structure of SF2457 was determined by degradation studies using alkaline hydrolysis and methanolysis. SF2457 is closely related to the amicetin group antibiotics. The antibiotic exhibited inhibitory activity against Gram-positive and Gram-negative bacteria.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
