Sibanomicin
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Category | Antibiotics |
Catalog number | BBF-02909 |
CAS | 117782-84-0 |
Molecular Weight | 429.51 |
Molecular Formula | C23H31N3O5 |
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Description
It is produced by the strain of Micronconospora sp. SF2364. It has weak effect against gram-positive bacteria. Mice inoculated with leukemic P388 cells were given 2.1 and 1.0 mg/kg, which extended the survival time by 96% and 69% compared with the control group.
Specification
Related CAS | 119180-42-6 (hydrochloride) |
Synonyms | 7-[[3-C-Methyl-4-(methylamino)-4,6-dideoxy-α-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-[(E)-propylidene]-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one; 5H-Pyrrolo[2,1-c][1,4]benzodiazepin-5-one, 7-[[4,6-dideoxy-3-C-methyl-4-(methylamino)-a-L-mannopyranosyl]oxy]-1,2,3,11a-tetrahydro-2-propylidene-, (2E)-; Antibiotic SF 2364 |
IUPAC Name | (8E)-2-[(2S,3R,4R,5S,6S)-3,4-dihydroxy-4,6-dimethyl-5-(methylamino)oxan-2-yl]oxy-8-propylidene-7,9-dihydro-6aH-pyrrolo[2,1-c][1,4]benzodiazepin-11-one |
Canonical SMILES | CCC=C1CC2C=NC3=C(C=C(C=C3)OC4C(C(C(C(O4)C)NC)(C)O)O)C(=O)N2C1 |
InChI | InChI=1S/C23H31N3O5/c1-5-6-14-9-15-11-25-18-8-7-16(10-17(18)21(28)26(15)12-14)31-22-20(27)23(3,29)19(24-4)13(2)30-22/h6-8,10-11,13,15,19-20,22,24,27,29H,5,9,12H2,1-4H3/b14-6+/t13-,15?,19-,20-,22-,23+/m0/s1 |
InChI Key | JEZZKSQFJNWDCY-ZQBBTFQLSA-N |
Properties
Appearance | Colorless Amorphous Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria; Neoplastics (Tumor) |
Boiling Point | 666.2°C at 760 mmHg |
Melting Point | 185-195°C (dec.) |
Density | 1.36 g/cm3 |
Solubility | Soluble in Water, DMSO, Butanol, Methanol |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2