SNF-4435D
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Category | Antibiotics |
Catalog number | BBF-02478 |
CAS | |
Molecular Weight | 477.5 |
Molecular Formula | C28H31NO6 |
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Description
SNF-4435D is a nitrophenyl pyrone isolated from the culture broth of an actinomycete strain SNF4435. It is active against staphylococcus, mycobacteria, Candida albicans and Pyricularia oryzae. It shows a potent immunosuppressive activity in vitro and selectively suppresses B-cell proliferation induced by LPS versus T-cell proliferation induced by Con A.
Specification
Synonyms | SNF4435D |
IUPAC Name | 2-methoxy-3,5-dimethyl-6-[(1R,2'S,6S,7S,8R)-1,3,5-trimethyl-8-(4-nitrophenyl)spiro[bicyclo[4.2.0]octa-2,4-diene-7,4'-oxolane]-2'-yl]pyran-4-one |
Canonical SMILES | CC1=CC(=CC2(C1C3(C2C4=CC=C(C=C4)[N+](=O)[O-])CC(OC3)C5=C(C(=O)C(=C(O5)OC)C)C)C)C |
InChI | InChI=1S/C28H31NO6/c1-15-11-16(2)24-27(5,12-15)25(19-7-9-20(10-8-19)29(31)32)28(24)13-21(34-14-28)23-17(3)22(30)18(4)26(33-6)35-23/h7-12,21,24-25H,13-14H2,1-6H3/t21-,24-,25+,27+,28-/m0/s1 |
InChI Key | DXCYJJKWPZZHNZ-KAKVGEDNSA-N |
Properties
Appearance | Pale Yellow Powder |
Antibiotic Activity Spectrum | Gram-positive bacteria; neoplastics (Tumor); mycobacteria |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2