SO-75R1
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| Category | Antibiotics |
| Catalog number | BBF-02483 |
| CAS | 143458-82-6 |
| Molecular Weight | 558.66 |
| Molecular Formula | C29H34O11 |
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Description
SO-75R1 is a mutactimycin derivative produced by Nocardia brasiliensis. It inhibits gram-positive bacteria with MIC of 0.2-3.1 μg/mL, and inhibits L1210 cell with ED50 of 7.4 μg/mL.
Specification
| Synonyms | SO 75R1; SO-075R1 |
| IUPAC Name | 6,9,11-trihydroxy-7-(3-hydroxy-4,5-dimethoxy-6-methyloxan-2-yl)oxy-4-methoxy-3,9-dimethyl-8,10-dihydro-7H-tetracene-5,12-dione |
| Canonical SMILES | CC1C(C(C(C(O1)OC2CC(CC3=C2C(=C4C(=C3O)C(=O)C5=C(C4=O)C(=C(C=C5)C)OC)O)(C)O)O)OC)OC |
| InChI | InChI=1S/C29H34O11/c1-11-7-8-13-17(25(11)36-4)23(33)19-18(20(13)30)21(31)14-9-29(3,35)10-15(16(14)22(19)32)40-28-24(34)27(38-6)26(37-5)12(2)39-28/h7-8,12,15,24,26-28,31-32,34-35H,9-10H2,1-6H3 |
| InChI Key | BOCNMPJNEZKZFJ-UHFFFAOYSA-N |
Properties
| Appearance | Orange Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 121-122°C |
Reference Reading
1. The producer and biological activities of SO-75R1, a new mutactimycin group antibiotic [corrected]
A Maeda, K Yazawa, Y Mikami, M Ishibashi, J Kobayashi J Antibiot (Tokyo). 1992 Dec;45(12):1848-52. doi: 10.7164/antibiotics.45.1848.
The producer of SO-75R1, a new anthracycline group antibiotic was identified as Nocardia brasiliensis. SO-75R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant to SO-75R1, although four other pathogenic Nocardia, i.e. N. asteroides, N. nova, N. farcinica and N. otitidiscaviarum were sensitive [corrected].
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
