SW-163B
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| Category | Bioactive by-products |
| Catalog number | BBF-02487 |
| CAS | |
| Molecular Weight | 656.7 |
| Molecular Formula | C33H40N2O12 |
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Description
SW-163B is an immunosuppressant isolated from the culture broth of Streptomyces sp. SNA15896. It showed immunosuppressive and antimicrobial activities in vitro.
Specification
| Synonyms | SW-163 B |
| IUPAC Name | N-(15-benzyl-14-hydroxy-3,7,13,13-tetramethyl-2,5,9,12-tetraoxo-10-propan-2-yl-1,4,8,11-tetraoxacyclopentadec-6-yl)-3-formamido-2-hydroxybenzamide |
| Canonical SMILES | CC1C(C(=O)OC(C(=O)OC(C(C(C(=O)OC(C(=O)O1)C(C)C)(C)C)O)CC2=CC=CC=C2)C)NC(=O)C3=C(C(=CC=C3)NC=O)O |
| InChI | InChI=1S/C33H40N2O12/c1-17(2)26-31(42)44-18(3)24(35-28(39)21-13-10-14-22(25(21)37)34-16-36)30(41)45-19(4)29(40)46-23(15-20-11-8-7-9-12-20)27(38)33(5,6)32(43)47-26/h7-14,16-19,23-24,26-27,37-38H,15H2,1-6H3,(H,34,36)(H,35,39) |
| InChI Key | KHAIDUWWKKROCZ-UHFFFAOYSA-N |
Properties
| Appearance | White Powder |
Reference Reading
1. SW-163A and B, novel immunosuppressants produced by Streptomyces sp
K Takahashi, E Tsuda, K Kurosawa J Antibiot (Tokyo). 2001 Nov;54(11):867-73. doi: 10.7164/antibiotics.54.867.
SW-163A and B, novel immunosuppressants, were isolated from the culture broth of Streptomyces sp. SNA15896. The molecular formulas of SW-163A and B were determined as C34H42N2O12 and C33H40N2O12 based on the HRFAB-MS analysis, respectively. Both compounds were elucidated to be a large ring ester structure through spectroscopic analyses including various NMR measurements. SW-163A and B showed immunosuppressive and antimicrobial activities in vitro.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
