TMC-135B
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| Category | Mycotoxins |
| Catalog number | BBF-02540 |
| CAS | |
| Molecular Weight | 719.9 |
| Molecular Formula | C39H49N3O8S |
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Description
TMC-135B is a triene-ansamycin antibiotic produced by Streptomyces sp. TC 1190. It is cytotoxic to HCT-116, SK-BR-3, HeLa S3, WiDr, HT29 and HL-60.
Specification
| Synonyms | TMC-135 B |
| IUPAC Name | [(6E,8E,10E,16Z)-15,28-dihydroxy-5-methoxy-14,16-dimethyl-3,24-dioxo-22-thia-2,25-diazatricyclo[18.7.1.021,26]octacosa-1(27),6,8,10,16,20(28),21(26)-heptaen-13-yl] 1-(cyclohexene-1-carbonylamino)cyclopropane-1-carboxylate |
| Canonical SMILES | CC1C(CC=CC=CC=CC(CC(=O)NC2=CC3=C(C(=C2O)CCC=C(C1O)C)SCC(=O)N3)OC)OC(=O)C4(CC4)NC(=O)C5=CCCCC5 |
| InChI | InChI=1S/C39H49N3O8S/c1-24-13-12-17-28-35(46)29(22-30-36(28)51-23-33(44)41-30)40-32(43)21-27(49-3)16-10-5-4-6-11-18-31(25(2)34(24)45)50-38(48)39(19-20-39)42-37(47)26-14-8-7-9-15-26/h4-6,10-11,13-14,16,22,25,27,31,34,45-46H,7-9,12,15,17-21,23H2,1-3H3,(H,40,43)(H,41,44)(H,42,47)/b5-4+,11-6+,16-10+,24-13- |
| InChI Key | YIMYDHUFVYSTEY-WUWQZELJSA-N |
Properties
| Appearance | Pale Yellow Powder |
| Antibiotic Activity Spectrum | neoplastics (Tumor) |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
