TMC-154
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| Category | Mycotoxins |
| Catalog number | BBF-02541 |
| CAS | |
| Molecular Weight | 789 |
| Molecular Formula | C41H72O14 |
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Description
TMC-154 is an antibiotic produced by Gliocladium sp. TC 1282. It has cytotoxicity to cancer cells like HCT-1l6, H-60, U937, WiDr.
Specification
| Synonyms | TMC 154 |
Properties
| Appearance | Solid Powder |
| Antibiotic Activity Spectrum | neoplastics (Tumor) |
| Melting Point | 70-77°C (dec.) |
Reference Reading
1. TMC-171A,B,C and TMC-154, novel polyketide antibiotics produced by Gliocladium sp. TC 1304 and TC 1282
J Kohno, Y Asai, M Nishio, M Sakurai, K Kawano, H Hiramatsu, N Kameda, N Kishi, T Okuda, S Komatsubara J Antibiot (Tokyo). 1999 Dec;52(12):1114-23. doi: 10.7164/antibiotics.52.1114.
Four new antibiotics, TMC-171A (2), B (3), C (4) and TMC-154 (5) have been isolated from the fermentation of fungal strains Gliocladium sp. TC 1304 and TC 1282, respectively. Spectroscopic and degradation studies have shown that TMC-171s and TMC-154 were new members of the TMC-151 class of antibiotics, unique polyketides modified with a D-mannose and a D-mannitol or a D-arabitol. These compounds showed moderate cytotoxicity to various tumor cell lines.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
