TMC-260
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Enzyme inhibitors |
| Catalog number | BBF-02548 |
| CAS | |
| Molecular Weight | 325.4 |
| Molecular Formula | C17H27NO5 |
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Capabilities & Facilities
Fermentation Lab
4 R&D and scale-up labs
2 Preparative purification labs
Fermentation Plant
Semi pilot, pilot and industrial plant 4 Manufacturing sites 7 Production lines at pilot scale 100+ Reactors of 30-4000 L; 170+ reactors of 20 KL-30 KL; 24+ reactors of >100 KL 2 Hydrogenation reactors (200 L, 4Mpa and 1000L, 4Mpa)
Product Description
TMC-260 is an inhibitor of IL-4 signal transduction produced by Acremonium kiliense Grütz TC 1703. It inhibited the IL-4 driven luciferase activity with IC50 values of 9 μmol/L.
- Specification
- Properties
- Price Product List
| Synonyms | TMC 260 |
| IUPAC Name | (3S,4S,5S)-3-[(E)-3-[(2S,3S)-3-heptyloxiran-2-yl]prop-2-enoyl]-3,4-dihydroxy-5-methylpyrrolidin-2-one |
| Canonical SMILES | CCCCCCCC1C(O1)C=CC(=O)C2(C(C(NC2=O)C)O)O |
| InChI | InChI=1S/C17H27NO5/c1-3-4-5-6-7-8-12-13(23-12)9-10-14(19)17(22)15(20)11(2)18-16(17)21/h9-13,15,20,22H,3-8H2,1-2H3,(H,18,21)/b10-9+/t11-,12-,13-,15-,17+/m0/s1 |
| InChI Key | ZITQOKSHWTVTEJ-CBLWTXHFSA-N |
| Appearance | Solid Powder |
| Melting Point | 140-144°C |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
