TMC-260

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Category Enzyme inhibitors
Catalog number BBF-02548
CAS
Molecular Weight 325.4
Molecular Formula C17H27NO5

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Description

TMC-260 is an inhibitor of IL-4 signal transduction produced by Acremonium kiliense Grütz TC 1703. It inhibited the IL-4 driven luciferase activity with IC50 values of 9 μmol/L.

Specification

Synonyms TMC 260
IUPAC Name (3S,4S,5S)-3-[(E)-3-[(2S,3S)-3-heptyloxiran-2-yl]prop-2-enoyl]-3,4-dihydroxy-5-methylpyrrolidin-2-one
Canonical SMILES CCCCCCCC1C(O1)C=CC(=O)C2(C(C(NC2=O)C)O)O
InChI InChI=1S/C17H27NO5/c1-3-4-5-6-7-8-12-13(23-12)9-10-14(19)17(22)15(20)11(2)18-16(17)21/h9-13,15,20,22H,3-8H2,1-2H3,(H,18,21)/b10-9+/t11-,12-,13-,15-,17+/m0/s1
InChI Key ZITQOKSHWTVTEJ-CBLWTXHFSA-N

Properties

Appearance Solid Powder
Melting Point 140-144°C

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L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
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