TPU-0031-B

TPU-0031-B

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category Antibiotics
Catalog number BBF-02551
CAS
Molecular Weight 598.6
Molecular Formula C30H34N2O11

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Description

TPU-0031-B is an antibiotic of the novobiocin group produced by Streptomyces sp. TP-A0556. It shows antibiotic activity against Gram-positive and -negative bacteria.

Specification

IUPAC Name [(2R,3S,4R,5R,6R)-3-hydroxy-2-[4-hydroxy-3-[[4-hydroxy-3-(3-methylbut-2-enyl)benzoyl]amino]-8-methyl-2-oxochromen-7-yl]oxy-5-methoxy-6-methyloxan-4-yl] carbamate
Canonical SMILES CC1C(C(C(C(O1)OC2=C(C3=C(C=C2)C(=C(C(=O)O3)NC(=O)C4=CC(=C(C=C4)O)CC=C(C)C)O)C)O)OC(=O)N)OC
InChI InChI=1S/C30H34N2O11/c1-13(2)6-7-16-12-17(8-10-19(16)33)27(36)32-21-22(34)18-9-11-20(14(3)24(18)42-28(21)37)41-29-23(35)26(43-30(31)38)25(39-5)15(4)40-29/h6,8-12,15,23,25-26,29,33-35H,7H2,1-5H3,(H2,31,38)(H,32,36)/t15-,23+,25-,26-,29-/m1/s1
InChI Key ZYFOUWFPBOFFGB-KUFHLPEQSA-N

Properties

Appearance Solid Powder
Antibiotic Activity Spectrum Gram-positive bacteria; Gram-negative bacteria
Melting Point 179-180°C

Reference Reading

1. TPU-0031-A and B, new antibiotics of the novobiocin group produced by Streptomyces sp. TP-A0556
T Sasaki, Y Igarashi, N Saito, T Furumai J Antibiot (Tokyo). 2001 May;54(5):441-7. doi: 10.7164/antibiotics.54.441.
Two novel antibiotics, TPU-0031-A and B, were isolated from the culture broth of an actinomycete strain. The producing strain, TP-A0556, was identified as Streptomyces sp. based on the taxonomic study. The new antibiotics were obtained by solvent extraction and chromatographic purification. Spectroscopic analyses showed that TPU-0031-A and B were 7'-demethylnovobiocin and 5"-demethylnovobiocin, respectively. These compounds showed antibiotic activity against Gram-positive and -negative bacteria.

Bio Calculators

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

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