TPU-0037C
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| Category | Antibiotics |
| Catalog number | BBF-04606 |
| CAS | 485815-61-0 |
| Molecular Weight | 825.09 |
| Molecular Formula | C46H72N4O9 |
| Purity | >95% by HPLC |
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Description
A close structural analogue of lydicamycin produced by the marine actinomycete Streptomyces platensis. It has antibacterial activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). It is closely related to BU-4514N which is isolated from a strain of microtetraspora as a neuritogenic agent.
Specification
| Synonyms | Antibiotic TPU-0037C; 8-Dehydroxy-30-demethyllydicamycin; (+)-2-[21-[1-[(2,5-Dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)carbonyl]-1,2,4a,5,6,7,8,8a-octahydro-5-hydroxy-1,3-dimethyl-2-naphthalenyl]-2,6,10,14,18-pentahydroxy-11,17,19-trimethyl-4,8,12,16-heneicosatetraen-1-yl]-1-pyrrolidinecarboximidamide |
| Storage | Store at -20°C |
| IUPAC Name | 2-[(4E,8E,12E,16E)-21-[1-[(E)-(2,4-dioxopyrrolidin-3-ylidene)-hydroxymethyl]-5-hydroxy-1,3-dimethyl-4a,5,6,7,8,8a-hexahydro-2H-naphthalen-2-yl]-2,6,10,14,18-pentahydroxy-11,17,19-trimethylhenicosa-4,8,12,16-tetraenyl]pyrrolidine-1-carboximidamide |
| Canonical SMILES | CC1=CC2C(CCCC2O)C(C1CCC(C)C(C(=CCC(C=CC(C)C(C=CCC(C=CCC(CC3CCCN3C(=N)N)O)O)O)O)C)O)(C)C(=C4C(=O)CNC4=O)O |
| InChI | InChI=1S/C46H72N4O9/c1-27(38(54)15-7-12-32(51)11-6-13-34(53)25-31-10-9-23-50(31)45(47)48)17-20-33(52)21-18-28(2)42(57)29(3)19-22-36-30(4)24-35-37(14-8-16-39(35)55)46(36,5)43(58)41-40(56)26-49-44(41)59/h6-7,11,15,17-18,20,24,27,29,31-39,42,51-55,57-58H,8-10,12-14,16,19,21-23,25-26H2,1-5H3,(H3,47,48)(H,49,59)/b11-6+,15-7+,20-17+,28-18+,43-41+ |
| InChI Key | ABOXJBHGJDKUNW-OZIHTJRTSA-N |
| Source | Streptomyces sp. |
Properties
| Appearance | Colorless Film |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 161-163°C |
| Density | 1.3±0.1 g/cm3 |
| Solubility | Soluble in Ethanol, Methanol, DMF, DMSO; Poorly soluble in Water |
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
