UK-80695

* Please be kindly noted products are not for therapeutic use. We do not sell to patients.

Category Others
Catalog number BBF-03714
CAS 127346-86-5
Molecular Weight 654.83
Molecular Formula C38H54O9

Online Inquiry

Description

UK-80695 is a melbemycin antibiotic produced by Streptomyces hygroscopicus. It possesses anthelmintic and ectoparasiticidal activity.

Specification

Synonyms UK 80695; Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-13-(2-methyl-1-oxopropoxy)-25-(1-methyl-1-propenyl)-, (6R,13R,25S)-
IUPAC Name [(4S,5'S,6R,6'S,8R,10E,13S,14E,16E,20R,21R,24S)-6'-[(E)-but-2-en-2-yl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxospiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-12-yl] 2-methylpropanoate
Canonical SMILES CC=C(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC(=O)C(C)C)C)C
InChI InChI=1S/C38H54O9/c1-9-22(4)33-25(7)15-16-37(47-33)19-29-18-28(46-37)14-13-24(6)32(45-35(40)21(2)3)23(5)11-10-12-27-20-43-34-31(39)26(8)17-30(36(41)44-29)38(27,34)42/h9-13,17,21,23,25,28-34,39,42H,14-16,18-20H2,1-8H3/b11-10+,22-9+,24-13+,27-12+/t23-,25-,28+,29-,30?,31+,32?,33+,34+,37+,38+/m0/s1
InChI Key XQJPRIJOJVJRFC-VYLBHDSBSA-N

Properties

Antibiotic Activity Spectrum parasites
Boiling Point 787.9°C at 760 mmHg
Density 1.2 g/cm3

Reference Reading

1. C-13 beta-acyloxymilbemycins, a new family of macrolides. Discovery, structural determination and biological properties
M A Haxell, B F Bishop, P Bryce, K A Gration, H Kara, R A Monday, M S Pacey, D A Perry, Y Kojima, H Maeda, et al. J Antibiot (Tokyo). 1992 May;45(5):659-70. doi: 10.7164/antibiotics.45.659.
A family of novel milbemycins possessing C-13 beta-acyloxy substitution was produced by Streptomyces hygroscopicus ATCC 53718. These compounds were detected by HPLC diode array analysis and possess anthelmintic and ectoparasiticidal activity. The origin of the oxygen atom at C-13 is discussed.

Recommended Products

Bio Calculators

Stock concentration: *
Desired final volume: *
Desired concentration: *

L

* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2

* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O c22h30n40
g/mol
g

Recently viewed products

Online Inquiry

Verification code

Copyright © 2024 BOC Sciences. All rights reserved.

cartIcon
Inquiry Basket