Voriconazole
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| Category | Bioactive by-products |
| Catalog number | BBF-04154 |
| CAS | 137234-62-9 |
| Molecular Weight | 349.31 |
| Molecular Formula | C16H14F3N5O |
| Purity | >98% |
Ordering Information
| Catalog Number | Size | Price | Stock | Quantity |
|---|---|---|---|---|
| BBF-04154 | 10 g | $298 | In stock |
Online Inquiry
Add to cartDescription
Voriconazole is an antifungal medication used to treat a number of fungal infections, including aspergillosis, candidemia, and esophageal candidiasis.
Specification
| Synonyms | UK-109496; UK 109496; UK109496; UK109,496; UK-109,496; UK 109,496; Voriconazole; Vfend |
| Storage | Store at -20°C |
| IUPAC Name | (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol |
| Canonical SMILES | CC(C1=NC=NC=C1F)C(CN2C=NC=N2)(C3=C(C=C(C=C3)F)F)O |
| InChI | InChI=1S/C16H14F3N5O/c1-10(15-14(19)5-20-7-22-15)16(25,6-24-9-21-8-23-24)12-3-2-11(17)4-13(12)18/h2-5,7-10,25H,6H2,1H3/t10-,16+/m0/s1 |
| InChI Key | BCEHBSKCWLPMDN-MGPLVRAMSA-N |
Properties
| Appearance | White to Off-white Solid |
| Antibiotic Activity Spectrum | fungi |
| Boiling Point | 508.6±60.0°C at 760 mmHg |
| Melting Point | 129-132°C |
| Density | 1.4±0.1 g/cm3 |
| Solubility | Soluble in methanol, Acetonitrile |
Reference Reading
1.A retrospective analysis of patient-specific factors on voriconazole clearance.
Dote S1, Sawai M1, Nozaki A1, Naruhashi K2, Kobayashi Y1, Nakanishi H2. J Pharm Health Care Sci. 2016 Apr 19;2:10. doi: 10.1186/s40780-016-0044-9. eCollection 2016.
BACKGROUND: Voriconazole concentrations display a large variability, which cannot completely be explained by known factors. We investigated the relationships of voriconazole concentration with patient-specific variables and concomitant medication to identify clinical factors affecting voriconazole clearance.
2.Voriconazole pharmacokinetics following HSCT: results from the BMT CTN 0101 trial.
Hope WW1, Walsh TJ2, Goodwin J3, Peloquin CA4, Howard A5, Kurtzberg J6, Mendizabal A7, Confer DL8, Bulitta J9, Baden LR10, Neely MN11, Wingard JR4; Blood and Marrow Transplant Clinical Trials Network. J Antimicrob Chemother. 2016 Apr 27. pii: dkw127. [Epub ahead of print]
BACKGROUND: Voriconazole is a first-line agent for the prevention and treatment of a number of invasive fungal diseases. Relatively little is known about the relationship between drug exposure and the prevention of invasive fungal infections.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
