X-14873G
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| Category | Antibiotics |
| Catalog number | BBF-01669 |
| CAS | 88263-35-8 |
| Molecular Weight | 596.8 |
| Molecular Formula | C34H60O8 |
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Description
X-14873G is a polyether antibiotic produced by the fermentation of Streptomyces sp. X-14873. It is mainly active against Gram-positive bacteria.
Specification
| Synonyms | X 14873 G; X-14873 G; X14873 G |
| IUPAC Name | (3S,5S,6S,7S)-3-[(2S,3S,5S)-5-[(1R,3S,6R)-3,4-diethyl-6-methyl-2,7-dioxabicyclo[2.2.1]heptan-1-yl]-3,5-dimethyloxolan-2-yl]-7-[(2R,3S,4R,5R,6S)-5-ethyl-4,6-dihydroxy-3,6-dimethyloxan-2-yl]-6-hydroxy-5-methyloctan-4-one |
| Canonical SMILES | CCC1C(C(C(OC1(C)O)C(C)C(C(C)C(=O)C(CC)C2C(CC(O2)(C)C34C(CC(O3)(C(O4)CC)CC)C)C)O)C)O |
| InChI | InChI=1S/C34H60O8/c1-12-23(27(36)20(7)26(35)21(8)30-22(9)28(37)24(13-2)32(11,38)41-30)29-18(5)16-31(10,40-29)34-19(6)17-33(15-4,42-34)25(14-3)39-34/h18-26,28-30,35,37-38H,12-17H2,1-11H3/t18-,19+,20-,21-,22-,23+,24+,25-,26+,28+,29-,30+,31-,32-,33?,34+/m0/s1 |
| InChI Key | IVNOVETYABPCDY-FCOSVTLMSA-N |
Properties
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 152-153°C |
Reference Reading
1. Novel polyether antibiotics X-14873A, G and H produced by a Streptomyces: taxonomy of the producing culture, fermentation, biological and ionophorous properties of the antibiotics
C M Liu, J W Westley, T E Hermann, B L Prosser, N Palleroni, R H Evans, P A Miller J Antibiot (Tokyo). 1986 Dec;39(12):1712-8. doi: 10.7164/antibiotics.39.1712.
Novel polyether antibiotics X-14873A, X-14873G, and X-14873H are produced by the fermentation of Streptomyces sp. X-14873 (ATCC 31679). This report presents taxonomic studies and fermentation conditions for the antibiotic producing culture. The antibiotics are mainly active against Gram-positive bacteria. The ionophore properties of X-14873A are also characterized.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
