YM-32890 A
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| Category | Antibiotics |
| Catalog number | BBF-01684 |
| CAS | |
| Molecular Weight | 540.7 |
| Molecular Formula | C33H48O6 |
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Description
YM-32890 A is a macrolide antibiotic isolated from the fermentation broth of cytophaga sp. YL-02905S. It inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast.
Specification
| Synonyms | YM-32890A; YM-32890-A |
| IUPAC Name | (7E,15E,19E)-4,6,12,18-tetrahydroxy-21-methyl-10-methylidene-22-[(1E,3Z,5Z)-3-methylnona-1,3,5,8-tetraenyl]-1-oxacyclodocosa-7,15,19-trien-2-one |
| Canonical SMILES | CC1C=CC(CC=CCCC(CC(=C)CC=CC(CC(CC(=O)OC1C=CC(=CC=CCC=C)C)O)O)O)O |
| InChI | InChI=1S/C33H48O6/c1-5-6-7-9-13-25(2)18-21-32-27(4)19-20-28(34)15-10-8-11-16-29(35)22-26(3)14-12-17-30(36)23-31(37)24-33(38)39-32/h5,7-10,12-13,17-21,27-32,34-37H,1,3,6,11,14-16,22-24H2,2,4H3/b9-7-,10-8+,17-12+,20-19+,21-18+,25-13- |
| InChI Key | GXWAJHCYRDABLE-SMHIWBEXSA-N |
Properties
| Appearance | Syrup Matter |
Reference Reading
1. YM-32890 A and B, new types of macrolide antibiotics produced by Cytophaga sp
K Kamigiri, T Tokunaga, T Sugawara, K Nagai, M Shibazaki, B Setiawan, R M Rantiatmodjo, M Morioka, K Suzuki J Antibiot (Tokyo). 1997 Jul;50(7):556-61. doi: 10.7164/antibiotics.50.556.
Two new types of macrolide antibiotics, YM-32890 A and B, have been isolated from the fermentation broth of cytophaga sp. YL-02905S. In this paper, the taxonomy of the producing strain, fermentation, isolation, structure elucidation, and biological activity of the antibiotics are reported. YM-32890 A inhibits the growth of staphylococci including a macrolide-resistant strain, but shows no antimicrobial activity against other Gram-positive, Gram-negative bacteria and yeast.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
