Zg
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| Category | Others |
| Catalog number | BBF-01566 |
| CAS | |
| Molecular Weight | 410.4 |
| Molecular Formula | C22H18O8 |
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Description
Zg is a red quinone piment produced from Streptomyces Thermoviolaceus sub sp. pigens var WR-141.
Specification
| IUPAC Name | (4S,8S,10S)-2,12-dihydroxy-16-(1-hydroxyethyl)-10-methyl-5,9-dioxapentacyclo[11.8.0.03,11.04,8.015,20]henicosa-1,3(11),12,15(20),16,18-hexaene-6,14,21-trione |
| Canonical SMILES | CC1C2=C(C3C(O1)CC(=O)O3)C(=C4C(=C2O)C(=O)C5=C(C4=O)C=CC=C5C(C)O)O |
| InChI | InChI=1S/C22H18O8/c1-7(23)9-4-3-5-10-14(9)20(27)16-15(18(10)25)21(28)17-13(19(16)26)8(2)29-11-6-12(24)30-22(11)17/h3-5,7-8,11,22-23,26,28H,6H2,1-2H3/t7?,8-,11-,22+/m0/s1 |
| InChI Key | CIVDMICROXQXLC-KHTJLTNQSA-N |
Properties
| Melting Point | 241-248°C |
Reference Reading
1. Rosette morphology in zona glomerulosa formation and function
Sining Leng, Diana L Carlone, Nick A Guagliardo, Paula Q Barrett, David T Breault Mol Cell Endocrinol. 2021 Jun 15;530:111287. doi: 10.1016/j.mce.2021.111287. Epub 2021 Apr 21.
How morphology informs function is a fundamental biological question. Here, we review the morphological features of the adrenal zona glomerulosa (zG), highlighting recent cellular and molecular discoveries that govern its formation. The zG consists of glomeruli enwrapped in a Laminin-β1-enriched basement membrane (BM). Within each glomerulus, zG cells are organized as rosettes, a multicellular structure widely used throughout development to mediate epithelial remodeling, but not often found in healthy adult tissues. Rosettes arise by constriction at a common cellular contact point mediated/facilitated by adherens junctions (AJs). In mice, small, dispersed AJs first appear postnatally and enrich along the entire cell-cell contact around 10 days after birth. Subsequently, these AJ-rich contacts contract, allowing rosettes to form. Concurrently, flat sheet-like domains in the nascent zG, undergo invagination and folding, gradually giving rise to the compact round glomeruli that comprise the adult zG. How these structures impact adrenal function is discussed.
2. Nonalcoholic Fatty Liver Disease: An Emerging Driver of Hypertension
Yan-Ci Zhao, Guo-Jun Zhao, Ze Chen, Zhi-Gang She, Jingjing Cai, Hongliang Li Hypertension. 2020 Feb;75(2):275-284. doi: 10.1161/HYPERTENSIONAHA.119.13419. Epub 2019 Dec 23.
Hypertension, a multifactorial disorder resulting from the interplay between genetic predisposition and environmental risk factors, affects ≈30% of adults. Emerging evidence has shown that nonalcoholic fatty liver disease (NAFLD), as an underestimated metabolic abnormality, is strongly associated with an increased risk of incident prehypertension and hypertension. However, the role of NAFLD in the development of hypertension is still obscure and is highly overlooked by the general public. Herein, we highlight the epidemiological evidence and putative mechanisms focusing on the emerging roles of NAFLD in hypertension, with the purpose of reinforcing the notion that NAFLD may serve as an independent risk factor and an important driving force in the development and progression of hypertension. Finally, we also briefly summarize the current potential treatments for NAFLD that might also be beneficial approaches against hypertension.
3. Optimization and Chemical Characterization of Biosurfactant Produced from a Novel Pseudomonas guguanensis Strain Iraqi ZG.K.M
Zeena Ghazi Faisal, Mayaada Sallal Mahdi, Khalid H Alobaidi Int J Microbiol. 2023 Feb 1;2023:1571991. doi: 10.1155/2023/1571991. eCollection 2023.
Microbial surfactants are widely used in medical, pharmaceutical, agricultural, industrial, food, and cosmetics applications. In the present study, 85 indigenous bacteria were isolated from petroleum-contaminated soils of the Al Dourah refinery, electric power station, and electric generators in Baghdad, Iraq. Twenty nine isolates gave positive results in both blood agar and blue agar medium and were secondarily screened. One isolate was selected as a potent biosurfactant producer and molecularly identified and recorded in the NCBI GenBank nucleotide sequence database as Pseudomonas guguanensis strain Iraqi ZG.K.M. In optimized conditions, this strain can produce about 3.01 g/l of biosurfactant. The product could reduce the surface tension from 72 to 38 ± 0.33 mN/m and have E24% of 52 ± 0.33%. This biosurfactant was preliminarily specified to be a glycolipid and characterized as a rhamnolipid with anionic nature, usually to be a monorhamnolipid as evident from TLC, FTIR, and GC-MS analyses.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
