β-Carotene

β-Carotene

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β-Carotene
Category Raw Materials of Healthcare Products
Catalog number BBF-05876
CAS 7235-40-7
Molecular Weight 536.87
Molecular Formula C40H56
Purity Content: 96.0-101.0%

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Description

β-Carotene is an organic compound and classified as a terpenoid. It is a precursor (inactive form) of vitamin A. β-carotene is widely used in the food industry, feed industry, medicine and cosmetics industry. β-carotene is an important part of the non-enzymatic defense mechanism against free radicals, which can effectively slow down aging while protecting against UV damage. In addition, it can whiten spots and have blue light protection effect. It can be widely used in anti-aging, wrinkle removal, firming and tender skin, whitening, light spot, sun protection, anti-blue light and other products, and it is compatible with lotion cream formula, gel formula and water formula.

Specification

Synonyms Beta-carotene; (all-E)-1,1'-(3,7,12,16-Tetramethyl-1,3,5,7,9,11,13,15,17-octadecanonaene-1,18-diyl)bis[2,6,6-trimethylcyclohexene]; β,β-Carotene; all-trans-β-Carotene; BetaVit; Betacarotene; Carotaben; NSC 62794; Provatene; Provatenol; Rovimix β-Carotene
Storage Cool, Darkness & Dry
IUPAC Name 1,3,3-trimethyl-2-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-3,7,12,16-tetramethyl-18-(2,6,6-trimethylcyclohexen-1-yl)octadeca-1,3,5,7,9,11,13,15,17-nonaenyl]cyclohexene
Canonical SMILES CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2=C(CCCC2(C)C)C)C)C
InChI InChI=1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
InChI Key OENHQHLEOONYIE-JLTXGRSLSA-N

Properties

Appearance Red to Dark Brown Solid
Application Ingredient of health care products.
Boiling Point 654.7±22.0°C at 760 mmHg
Melting Point 178-179°C
Flash Point 346°C
Density 0.9±0.1 g/cm3
Solubility Soluble in Chloroform (Slightly), Hexanes (Slightly), Methanol (Slightly)
LogP 12.60580

Reference Reading

1.Structural analysis, and antioxidant and antibacterial properties of chitosan-poly (vinyl alcohol) biodegradable films.
Hajji S1, Chaker A2, Jridi M3, Maalej H3, Jellouli K3, Boufi S2, Nasri M3. Environ Sci Pollut Res Int. 2016 Apr 23. [Epub ahead of print]
The development and characterization of biodegradable blend films based on chitosan and poly (vinyl alcohol) for possible use in a variety of biological activities are reported. Fourier transform infrared spectroscopy (FTIR) spectra of chitosan-poly (vinyl alcohol) (Ch/PVA) films showed characteristics peaks shifting to a lower frequency range due to hydrogen bonding between -OH of PVA and -NH2 of chitosan. The chitosan and PVA polymers presented good compatibility. The morphology study of chitosan and composite films showed a compact and homogenous structure. The tensile strength and elongation at break increased with PVA content. In fact, the highest tensile strength and elongation at break (53.58 MPa and 454 %) occurs with pure PVA film. The results showed that PVA incorporation in the blends contributes to increase the intermolecular interactions, thus improving the mechanical properties. In addition, the prepared films demonstrated high antioxidant activities monitored by 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging, reducing power, and β-carotene bleaching activity.
2.Substrate specificity of purified recombinant chicken β-carotene 9,10-oxygenase (BCO2).
Dela Seña C1, Sun J1, Narayanasamy S1, Riedl KM1, Yuan Y1, Curley RW Jr1, Schwartz SJ1, Harrison EH2. J Biol Chem. 2016 May 3. pii: jbc.M116.723684. [Epub ahead of print]
Provitamin A carotenoids are oxidatively cleaved by β-carotene 15-15'-dioxygenase (BCO1) at the central 15-15' double bond to form retinal (vitamin A aldehyde). Another carotenoid oxygenase, β-carotene 9'-10'-oxygenase (BCO2) catalyzes the oxidative cleavage of carotenoids at the 9'-10' bond to yield an ionone and an apo-10'-carotenoid. Previously published substrate specificity studies of BCO2 have been conducted using crude lysates from bacteria or insect cells expressing recombinant BCO2. Our attempts to obtain active recombinant human BCO2 expressed in Escherichia coli were unsuccessful. We have expressed recombinant chicken BCO2 in the strain E.coli BL21-Gold (DE3) and purified the enzyme by cobalt ion affinity chromatography. Like BCO1, purified recombinant chicken BCO2 reacts with the provitamin A carotenoids β-carotene, α-carotene, and β-cryptoxanthin. Its catalytic activity with β-carotene as substrate is at least 10-fold lower than that of BCO1.
3.Chemical Profile and Antioxidant Properties of Extracts and Essential Oils from Citrus x limon (L.) Burm. cv Femminello Comune.
Loizzo MR1, Tundis R1, Bonesi M1, Di Sanzo G2, Verardi A3, Lopresto CG4, Pugliese A5, Menichini F1, Balducchi R2, Calabrò V3. Chem Biodivers. 2016 Apr 25. doi: 10.1002/cbdv.201500186. [Epub ahead of print]
Citrus x limon cv Femminello comune (Rutaceae) from Rocca Imperiale (Italy), one of the six PGI (Protected Geographical Indication) Italian lemon crops, has been recently received renewed interest. In this work, fresh and dried peels and leaves were extracted by using hydrodistillation, supercritical fluid extraction (SFE) and Soxhlet apparatus. Chemical profile was assessed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). Except for leaves extracts obtained by Soxhlet apparatus, the monoterpene hydrocarbons fraction dominated. Limonene, γ-terpinene and β-pinene were the main identified compounds. The antioxidant activity was investigated by using different in vitro assays namely DPPH, ABTS, FRAP and β-carotene bleaching test. In DPPH test the essential oil obtained by hydrodistillation of fresh peel exhibited the highest activity (IC50 of 1.17 mg/ml). Leaves extracted by SFE showed a good activity in both DPPH and β-carotene bleaching test with IC50 values of 2.
4.Carotenoid metabolism during bilberry (Vaccinium myrtillus L.) fruit development under different light conditions is regulated by biosynthesis and degradation.
Karppinen K1,2, Zoratti L1, Sarala M1, Carvalho E3, Hirsimäki J1, Mentula H1, Martens S3, Häggman H1, Jaakola L4,5. BMC Plant Biol. 2016 Apr 21;16(1):95. doi: 10.1186/s12870-016-0785-5.
BACKGROUND: Carotenoids are important pigments and precursors for central signaling molecules associated in fruit development and ripening. Carotenoid metabolism has been studied especially in the climacteric tomato fruit but the content of carotenoids and the regulation of their metabolism have been shown to be highly variable between fruit species. Non-climacteric berries of the genus Vaccinium are among the best natural sources of health-beneficial flavonoids but not studied previously for carotenoid biosynthesis.

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