Leucinostatin D
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Category | Antibiotics |
Catalog number | BBF-02253 |
CAS | 100334-47-2 |
Molecular Weight | 1104.47 |
Molecular Formula | C56H101N11O11 |
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Description
It is produced by the strain of Paecilomyces marquandii. It's a peptide antibiotic. It has anti-gram-positive bacterial and fungal effects. It has in vitro cytotoxic activity against HeLa 850, KB cells and sensitive leukemia cells P388 with ID50 of 1.00 ng/mL.
Specification
Synonyms | Paecilotoxin D; (4R)-N-[1-[[2-hydroxy-3-methyl-1-[2-[[3-methyl-1-[[3-methyl-1-[2-[2-[2-(1-methylaminopropan-2-ylcarbamoyl)ethylcarbamoyl]propan-2-ylcarbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]butyl]carbamoyl]propan-2-ylcarbamoyl]butyl]carbamoyl]-3-methyl-butyl]-4-methyl-1-[(E,4S)-4-methylhex-2-enoyl]pyrrolidine-2-carboxamide |
IUPAC Name | (4R)-N-[1-[[3-hydroxy-4-methyl-1-[[2-methyl-1-[[4-methyl-1-[[4-methyl-1-[[2-methyl-1-[[2-methyl-1-[[3-[1-(methylamino)propan-2-ylamino]-3-oxopropyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methyl-1-[(E,4S)-4-methylhex-2-enoyl]pyrrolidine-2-carboxamide |
Canonical SMILES | CCC(C)C=CC(=O)N1CC(CC1C(=O)NC(CC(C)C)C(=O)NC(C(C(C)C)O)C(=O)NC(C)(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NCCC(=O)NC(C)CNC)C |
InChI | InChI=1S/C56H101N11O11/c1-20-35(10)21-22-43(69)67-30-36(11)28-41(67)49(74)61-38(25-31(2)3)47(72)63-44(45(70)34(8)9)50(75)65-55(15,16)52(77)62-39(26-32(4)5)46(71)60-40(27-33(6)7)48(73)64-56(17,18)53(78)66-54(13,14)51(76)58-24-23-42(68)59-37(12)29-57-19/h21-22,31-41,44-45,57,70H,20,23-30H2,1-19H3,(H,58,76)(H,59,68)(H,60,71)(H,61,74)(H,62,77)(H,63,72)(H,64,73)(H,65,75)(H,66,78)/b22-21+/t35-,36+,37?,38?,39?,40?,41?,44?,45?/m0/s1 |
InChI Key | RDUJTYZLXJPVKP-YDZNBPEVSA-N |
Properties
Appearance | White Crystal |
Antibiotic Activity Spectrum | Gram-positive bacteria; Neoplastics (Tumor); Fungi |
Boiling Point | 1323.8°C at 760 mmHg |
Melting Point | 184-185°C |
Density | 1.106 g/cm3 |
Solubility | Soluble in Chloroform, Ethanol |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2