YM-202204
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Category | Antibiotics |
Catalog number | BBF-01559 |
CAS | |
Molecular Weight | 646.8 |
Molecular Formula | C37H58O9 |
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Description
YM-202204 is an antifungal antibiotic isolated from the culture broth of marine fungus Phoma sp. Q60596. It exhibited potent antifungal activities against Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus, and also inhibited glycosyl-phosphatidyl-inositol (GPI)-anchoring in yeast cells.
Specification
Synonyms | 6'-(2,8-Dihydroxy-1,5,7,9,13,15,17-heptamethyl-nonadeca-3,5,11,13-tetraenyl)-3,4,4'-trihydroxy-6-hydroxymethyl-3,4,5,6-tetrahydro-2H-[2,3']bipyranyl-2'-one |
IUPAC Name | 6-[(4E,6E,12E,14E)-3,9-dihydroxy-6,8,10,14,16,18-hexamethylicosa-4,6,12,14-tetraen-2-yl]-3-[3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]-4-hydroxypyran-2-one |
Canonical SMILES | CCC(C)CC(C)C=C(C)C=CCC(C)C(C(C)C=C(C)C=CC(C(C)C1=CC(=C(C(=O)O1)C2C(C(CC(O2)CO)O)O)O)O)O |
InChI | InChI=1S/C37H58O9/c1-9-21(2)15-24(5)16-22(3)11-10-12-25(6)34(42)26(7)17-23(4)13-14-29(39)27(8)32-19-30(40)33(37(44)46-32)36-35(43)31(41)18-28(20-38)45-36/h10-11,13-14,16-17,19,21,24-29,31,34-36,38-43H,9,12,15,18,20H2,1-8H3/b11-10+,14-13+,22-16+,23-17+ |
InChI Key | YGLKXOYPYOHGNS-YKCFUFIQSA-N |
Properties
Appearance | Yellow Thick Liquid |
Antibiotic Activity Spectrum | fungi; yeast |
Reference Reading
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
![](/bio-fermen.v1/images/Molecular-Weight-Calculato-4.png)