Rancinamycin III

Rancinamycin III

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Category Antibiotics
Catalog number BBF-02176
CAS 60925-60-2
Molecular Weight 174.15
Molecular Formula C7H10O5
Purity >97%

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Description

Rancinamycin III is an antibiotic that has antibacterial properties originally isolated from Str. lincolnensis.

Specification

Synonyms SCHEMBL16431322
IUPAC Name 3,4,5,6-tetrahydroxycyclohexene-1-carbaldehyde
Canonical SMILES C1=C(C(C(C(C1O)O)O)O)C=O
InChI InChI=1S/C7H10O5/c8-2-3-1-4(9)6(11)7(12)5(3)10/h1-2,4-7,9-12H
InChI Key KQQCGAKRCKYICB-UHFFFAOYSA-N

Reference Reading

1. Rancinamycins I, II, III and IV structural studies
A D Argoudelis, R W Sprague, S A Mizsak J Antibiot (Tokyo). 1976 Aug;29(8):787-96. doi: 10.7164/antibiotics.29.787.
Rancinamycins are secondary metabolites produced by Streptomyces lincolnensis in a sulfur-depleted culture medium. The structures (except stereochemistry) of the main components of the rancinamycin-complex were determined by the use of IR, UV, PMR, and CMR spectra.
2. Rancinamycins, metabolites produced by Streptomyces lincolnensis in sulfur-depleted media
A D Argoudelis, T R Pyke, R W Sprague J Antibiot (Tokyo). 1976 Aug;29(8):777-86. doi: 10.7164/antibiotics.29.777.
Rancinamycins I, II, III, and IV are secondary metabolites produced by Streptomyces lincolnensis in a sulfur-depleted culture medium. Rancinamycins I, and II, the main components of the mixture, show broad spectrum antibiotic activity in vitro. Subcutaneously injected or orally administered antibiotic afforded no protection for experimentally infected mice against lethal challenges of Staphylococcus aureus. Radioactive tracer studies failed to demonstrate that the rancinamycin were precursors in the biosynthesis of lincomycin.

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