Others

cyclo(L-Phe-L-Pro) is a diketopiperazine formed by the fusion of phenylalanine and proline, and is a secondary metabolite of fungi and bacteria. It can activate N-acyl homoserine lactone (ahls), and can also activate or counteract other Lux-based quorum sensing systems.

Anhydrochlortetracycline is an impurity in the tetracycline antibiotic chlortetracycline, which is formed from tetracycline in an acidic environment.

cyclo(L-Pro-L-Tyr) is a diketopiperazine formed by the fusion of tyrosine and proline, and is a secondary metabolite of fungi and bacteria. It can activate N-acyl homoserine lactone (ahls), and can also activate or counteract other luxr-based quorum sensing systems.

A metabolite of chlortetracycline, a tetracycline antibiotic.

Paclobutrazol is a triazole antifungal drug that inhibits the growth of plants by preventing the biosynthesis of gibberellin (a plant hormone).

Chaetoglobosin A, a sort of a mycotoxic cytochalasan compound, could be obtained from endophytic fungus C. globosum and has been found to exhibit antibacterial and nematicidal activities. It is also found to be effective in inducing apoptosis of cancer cells.

A metabolite of pretilachlor.

Bafilomycin C1 is a macrolide compound found in Streptomyces and an inhibitor of V-ATPase protein. It has a wide range of activities against bacteria, fungi, insects, and nematodes. It is a potential drug for the treatment of osteoporosis.

A quorum sensing agent, regulating bacterial cell density by balancing the levels of toxin and antitoxin via mazef-mediated cell death genes.

A sparingly soluble (1.2 mg/ml) sulfonylurea herbicidal agent.

A semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.

6-Benzylaminopurine, a purine-based first-generation synthetic cytokinin, which could stimulate plant growth.

(9S)-9-Deoxo-12-deoxy-9,12-epoxyerythromycin is a derivative of Erythromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by targeting the 55S ribosomal subunit, blocking the progression of nascent polypeptide chains.

A metabolite of Sulfamethoxazole.

Sodium pyruvate is the end product of glycolysis and is used for further metabolic cycles to provide energy for cells.

A freely soluble herbicide synthesized by streptomyces hygroscopicus and streptomyces viridochromeogenes.

The parent 4-nitrophenylpropylamine formed by the hydrolysis of the dichloroacetamide of chloramphenicol. It has no antibiotic activity but has played an integral role in the synthesis and SAR of new generation antibiotics, notably thiamphenicol and experimental analogues, bromamphenicol and methamphenicol.

Dihydrotanshinone I is isolated from the roots of Salvia miltiorrhiza Bge. It exhibits dose-dependent inhibition towards HLM-catalyzed propofol glucuronidation.

Diacetylphloroglucinol is a phenolic metabolite produced by bacteria, including Pseudomonas strains, and exhibits a wide range of biological activities, although the potency is mostly low.

4-Bromo-calcimycin, a halogenated analog of A-2318, is a non-fluorescent Ca2+ ionophore which could be commonly used in fluorescent probes experiments as a modutor of the quantitation of free Ca2+. Nonfluorescent calcium ionophore used as a calibration standard for determining cytoplasmic calcium ions by fluorescent probes.