Cefazolin
* Please be kindly noted products are not for therapeutic use. We do not sell to patients.
| Category | Antibiotics |
| Catalog number | BBF-00714 |
| CAS | 25953-19-9 |
| Molecular Weight | 454.51 |
| Molecular Formula | C14H14N8O4S3 |
| Purity | 98% |
Online Inquiry
Description
It is produced by the strain of Semisynthetic first generation cephalosporin for injection. The activity of Cefazolin to gram-positive bacteria was similar to Cefazolin and Cefazolin, but the activity of gram-negative bacteria was slightly stronger. After intramuscular injection, blood drug concentration increased (blood peak concentration is equivalent to 3-4 times of cefthiophene), and serum elimination half-life was 1.8h, mainly discharged in urine. It may also be used before and during certain surgeries to help prevent infection.
Specification
| Synonyms | Cephazolin; Cephamezine; Cefazoline; Cefamezin; Cephazoline; Cephazolidin; Cefazolina; Cefazolinum; Cefazolin acid; Elzogram; Kefzol; (6R-trans)-3-(((5-Methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-7-(((1H-tetrazol-1-yl)acetyl)-amino)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid; 7-(1-(1H-)-Tetrazolylacetamido)-3-(2-(5-methyl-1,3,4-thiadiazolyl)thiomethyl)delta3-cephem-4-carboxylic acid |
| Storage | 2-8 °C |
| IUPAC Name | (6R,7R)-3-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanylmethyl]-8-oxo-7-[[2-(tetrazol-1-yl)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
| Canonical SMILES | CC1=NN=C(S1)SCC2=C(N3C(C(C3=O)NC(=O)CN4C=NN=N4)SC2)C(=O)O |
| InChI | InChI=1S/C14H14N8O4S3/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26)/t9-,12-/m1/s1 |
| InChI Key | MLYYVTUWGNIJIB-BXKDBHETSA-N |
Properties
| Appearance | Colorless Acicular Crystal |
| Antibiotic Activity Spectrum | Gram-positive bacteria |
| Melting Point | 198-200 °C (dec.) |
| Density | 2.01±0.1 g/cm3 (Predicted) |
| Solubility | Freely soluble in DMF, Pyridine; Soluble in Aqueous Ethanol, Aqueous Acetone, Aqueous Dioxane; Slightly soluble in Methanol; Insoluble in Chloroform, Benzene, Ether |
Reference Reading
Recommended Products
| BBF-00764 | Cerebroside C | Inquiry |
| BBF-02614 | Nystatin | Inquiry |
| BBF-00677 | 3-Amino-3-deoxy-D-glucose | Inquiry |
| BBF-01829 | Deoxynojirimycin | Inquiry |
| BBF-03753 | Baicalin | Inquiry |
| BBF-01825 | Loganin | Inquiry |
Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
