Sch 484129
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| Category | Antibiotics |
| Catalog number | BBF-02438 |
| CAS | |
| Molecular Weight | 618.8 |
| Molecular Formula | C31H54O12 |
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Description
Sch 484129 is a glycolipid antibiotic isolated from the fermentation broth of Basidiomycete HAM-240. It displayed antifungal activity against Saccharomyces and Aspergillus strains.
Specification
| Synonyms | Sch-484129 |
| IUPAC Name | 11-[6-(acetyloxymethyl)-3-(2-carboxyacetyl)oxy-4,5-dihydroxyoxan-2-yl]oxyicosanoic acid |
| Canonical SMILES | CCCCCCCCCC(CCCCCCCCCC(=O)O)OC1C(C(C(C(O1)COC(=O)C)O)O)OC(=O)CC(=O)O |
| InChI | InChI=1S/C31H54O12/c1-3-4-5-6-8-11-14-17-23(18-15-12-9-7-10-13-16-19-25(33)34)41-31-30(43-27(37)20-26(35)36)29(39)28(38)24(42-31)21-40-22(2)32/h23-24,28-31,38-39H,3-21H2,1-2H3,(H,33,34)(H,35,36) |
| InChI Key | XVDLULKLSKWATQ-UHFFFAOYSA-N |
Properties
| Appearance | Oily Matter |
| Solubility | Soluble in methanol, chloroform. |
Reference Reading
1. Isolation and characterization of two new antifungal antibiotics from a basidiomycete
Min Chu, Ronald Mierzwa, Ling Xu, Ling He, Erik Langsdorf, Martha Beyazova, Joseph Terracciano, Mahesh Patel, Tze-Ming Chan, Vincent Gullo J Antibiot (Tokyo). 2003 Jan;56(1):9-15. doi: 10.7164/antibiotics.56.9.
Two novel antibiotics, Sch 484129 (1) and Sch 484130 (2), were isolated from the fermentation broth of a fungal culture, which was identified as a Basidiomycete. The new antibiotics were obtained by ethyl acetate extraction followed by reversed phase HPLC purification. Structure elucidation of 1 and 2 was accomplished by spectroscopic data analyses. Derivatizations of the major component 1 were performed in order to provide definitive structural information. Both components were identified as glycolipids and displayed antifungal activity against Saccharomyces and Aspergillus strains.
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Bio Calculators
* Our calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
It is commonly abbreviated as: C1V1 = C2V2
* Total Molecular Weight:
g/mol
Tip: Chemical formula is case sensitive. C22H30N4O √ c22h30n40 ╳
