Mycotoxins

Botryodiplodin is an antibiotic mycotoxin produced by Botryodiplodia theobromae. It has activity against gram-positive bacteria.

Brevetoxin 6 is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis).

Byssochlamic acid is a mycotoxin produced by Byssochlamys fulva (Paecilomyces variotii) and Bys. nivea.

Azinomycin A is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively.

Azinomycin B is produced by the strain of Streptomyces griseofuscus. It was highly cytotoxic, and the cytotoxicity of A and B to L5178Y cell IC50 was 0.07 g/mL and 0.11 g/mL, respectively.

Benesudon is produced by the strain of Mollisia benesuada. MIC 2.5-10μg/mL was found to be resistant to gram-positive bacteria, negative bacteria, yeast and fungi. It's cytotoxic and its IC50 of L1 210, RBL, BHK21 and B1 6-F1 cells is 1-2μg/mL.

It is produced by the strain of Sorangium cellulosum So ce12. Chivosazol A has anti-yeast and filamentous fungal activity and has strong toxicity to mammalian cells.

It is produced by the strain of Chondromyces crocatus. Chondramide A has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities.

It is produced by the strain of Chondromyces crocatus. Chondramide B has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities.

It is produced by the strain of Chondromyces crocatus. Chondramide C has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities.

It is produced by the strain of Chondromyces crocatus. Chondramide D has anti-candida, Henson yeast, lipids yeast, ball-like yeast and other fungal activities, but has no anti-gram positive and negative bacteria activities.

Chrymutasin A is produced by the strain of Streptomyces chartreusis D329. The IC50 of P388, Meth A, A549, MKN45 and WiDr cells were 0.76, 1.55, 4.25, 1.35 and 1.56 g/mL, respectively.

Chrymutasin B is produced by the strain of Streptomyces chartreusis D329. Chrymutasin B is cytotoxic.

Chrymutasin C is produced by the strain of Streptomyces chartreusis D329. Chrymutasin C is cytotoxic.

It is produced by the strain of Streptomyces cinereoruber var. fructo fermentans. Cinerubin A has anti-gram-positive bacteria, mycobacterium, fungis and amoeba activity, and has strong effect on mouse adenocarcinoma E0771.

It is produced by the strain of Streptomyces sp. DO-114. Clecarmycin C has anti-gram-positive bacteria activity with MIC 0.04-0.33μg/mL. It also showed strong cytotoxicity, with IC50 of 11.5 mg/mL against HeLa S3 cells, which was 10-20 times stronger than adriamycin.

Clitidine is produced by the strain of Clitocybe acromelalga. hypertoxic substance.

It is produced by the strain of Streptomyces sp. MRI 142. Aflatoxin A has anti-Gram-positive bacteria, Pyricularia oryzae and yeast activity (MIC is 0.19-0.39 µg/mL), and inhibits the growth of adenocarcinoma 755 (1.0 mg/kg reduces tumor growth by 75% the above).

It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees).

It is produced by the strain of Alternaria kikuchiana AS-1223. It's a plant toxin (especially for pear trees).