Bioactive by-products

Quinolactactin A is a quinolone fungal metabolite that inhibits TNF production induced by LPS in murine peritoneal macrophages.

Rasfonin is a fungal metabolite that has been found in Talaromyces sp. 3656-A1. It is a Ras-dependent apoptosis inducer that induces apoptosis in Ras-dependent cells such as Ba/F3-V12 cells.

Rhodopeptin C1 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively.

Rhodopeptin C2 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively.

Rhodopeptin C3 is a cyclic tetrapeptide originally isolated from Rhodococcus sp. Mer-N1033. It has anti-candida and cryptococcus neoformant activities, and the MIC (μg/mL) was 1.25~2.5 and 0.63~1.25, respectively.

Ripromycin is produced by the strain of Streptomyces sp Tu 6239. It has moderate anti-gram-positive bacterial activity, but not anti-gram-negative bacteria or fungi. It inhibited the proliferation of HM02 and MCF cells with IC50 of 1.6 and 2.0 μg/mL, respectively.

Roridin C is a fungal sesquiterpene derived from Myrothecium roridum S-1135 (NRRL 3005).

Roridin D is originally isolated from Myrothecium roridum S-1135 (NRRL 3005).

Roridin E is originally isolated from Myrothecium roridum S-1135 (NRRL 3005).

Roridin J is originally isolated from Myrothecium roridum S-1135 (NRRL 3005) and it has anti-leukemia effect in mice.

Roridin L2 is originally isolated from M. roridum var. and it has antibacterial and antitumor effects.

It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity. pH 6.5, The antibacterial activity of Pacidamycin 1 can be enhanced twice. In vivo test of mice infected with pseudomonas aeruginosa (100 mg/kg·d) showed no protective effect.

It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity.

It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity.

It is produced by the strain of Str. coeruleorubidus AB 1183F-64. It has inhibitory effect on Pseudomonas aeruginosa. It also has effect on a few strains of bacteria such as suppurative staphylococcus and Escherichia coli. Serum can reduce its antibacterial activity, pH also affects its antibacterial activity.

It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect.

It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect.

It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells.

It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect.

It is produced by the strain of Lachnum papyraceum. It has weak effect against nematodes and has inhibitory effect on L1210 and HL60 cells. It also has weak anti-gram-positive bacterial effect.