Others

It is produced by the strain of Str. viridochromogen. It is a protective agent of nerve cells and has the effect of reducing L-glutamate on cytotoxicity of neuronal hybridoma N18-RE-105 with ED50 of 15.5 nmol/L.

It is produced by the strain of Bacillus licheniformis IM 1307. It acts as a surfactant and is 10 times more active than Surfactin.

It is produced by the strain of Str. WK-4028. It has no inhibitory effect on testosterone 5α-reductase, and it has no anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast effects.

It is produced by the strain of Str. WK-4028. It has no inhibitory effect on testosterone 5α-reductase, and it has no anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast effects.

It is produced by the strain of Str. WK-4028. It has no inhibitory effect on testosterone 5α-reductase, and it has no anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast effects.

It is produced by the strain of Eupenicillium shearii F80965. It does not inhibit the biosynthesis of melanin and tyrosinase. It has antioxidant effect.

It is produced by the strain of Eupenicillium shearii F80965. It does not inhibit the biosynthesis of melanin and tyrosinase. It has antioxidant effect.

It is produced by the strain of Streptomyces coeruleorubidus NRRL 18370.

It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.34 μg/mL.

It is produced by the strain of Str. sp. 833. It is a phenazine Substance that has the protective effect of new neuron cells. It can scavenge free radicals, protect N18-RE 105 nerve cells from glutamate toxicity, and inhibit lipid peroxidation. It inhibits glutamate toxicity in N18-RE-105 cells with EC50 of 0.33 μg/mL.

It is produced by the strain of Streptomyces sp. 833. It can protect N18-RE-105 nerve cells from glutamate toxicity with EC50 of 0.37 μmol/L (similar to Phenazinastatin A) and inhibit lipid peroxidation. It has low toxicity, and 100 μmol/L of Phenazostatin C is not cytotoxic.

It is produced by the strain of Acremonium fusigerum. It's a substance that increases the expression of genes. 3 nmol/L - 1000 μmol/L of Phoenistatin causes more than 3 times the gene expression of the PA1-1 promoter.

It is produced by the strain of Str. sp. RK-16.

Monorden A is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity. It inhibits Hsp90 activity by binding to the ATP-binding pocket, thus suppressing cell transformation induced by src, ras and mos.

Monorden C is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity.

Monorden D is a metabolite of Humicola sp. FO-2942. It has the effect of arresting the cell cycle of Jurket cells in G1 and G2/M phases. It has anti-Aspergillus niger activity.

Myriocin is an unsaturated hydrocarbon and fatty acid derivative produced by Myriococcum albomyces NRRL 3858. It has antifungal activity.

Pyrocoll is a compound produced by Streptomyces sp. AK409 with antiparasitic and antitumor effects. It has activity against Arthrobacter bacteria, with an MIC of 1-10 μg/mL. It has a moderate anti-plasmodium effect, and its IC50 for Plasmodium facipaum is 1.19 μg/mL (standard chloroquine is 0.078 μg/mL). It also inhibits the growth of tumor cells. The IC50 pairs of HM02, HepG2 and MCF 7 cells are 0.23, 0.42 and 2.2 μg/mL, respectively.