Antibiotics

It is produced by the strain of Streptomyces sp. NK11687. It is a semisynthetic tetracycline. The antibacterial spectrum and antibacterial activity are the same as tetracycline, it is characterized by stronger affinity to bronchial and lung tissue than tetracycline, blood drug concentration is higher than tetracycline and lasting.

It is produced by the strain of Streptomyces hygroscopicus 662. It is a macrolide antibiotic. It has weak anti-gram-negative bacterial and fungal activity.

It is produced by the strain of Streptomyces hygroscopicus 662. It is a macrolide antibiotic. It has weak anti-gram-negative bacterial and fungal activity.

Guanine-7-oxide hydrochloride is produced by the strain of Streptomyces sp.. It has anti-tumor, anti-candida albicans activity, and can inhibit viral replication effect of herpes virus, infectious blood virus (IHNV), infectious pancreatic necrosis virus (IPNV) and so on. It has good activity against mouse L1210 leukemia cells.

It is produced by the strain of Ustilago sp. It is a quinone antibiotic. It has strong activity against gram-positive bacteria, negative bacteria and mycoplasma.

It is produced by the strain of Penicillum frequentans. It can inhibit adenosine and deoxyadenosine biosynthesis, and has significant inhibitory effects on human adenocarcinoma (HAD# 1), human adenocarcinoma-1, human epithelial carcinoma-3, and bronchial carcinoma-A42. It also has the activity of anti-gram-positive bacteria and negative bacteria, and can cause plant internode shortening, root growth stopping and flowering delay.

It is produced by the strain of Nectria haematococca Berk. et Br. (880701a-1). It can inhibit the germination of Pyricularia oryzae spore. 500 μg/mL of Haematocin culture 5h may inhibit 97.5% spore germination, but has no effect below 30 μg/mL.

It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest.

It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest.

It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest.

It is produced by the strain of Haliangium luteum AJ-13395, H. ochraceum. It is similar to amphotericin B with anti-filamentous fungi activity (MIC 0.1-12.5 μg/mL), and it also has effect on oomycetes, but has no antibacterial activity. The antifungal activity of cis-trans isomer is similar, the activity of Haliangicin B and C is weaker than Haliangicin A, and the activity of Haliangicin D is weakest.

It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual).

It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual).

It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual).

It is produced by the strain of Micromonospora halophytica var. nigra. It's an ansamycin antibiotic. Halomicin complex has activity against gram-positive and gram-negative bacteria (individual).

It is produced by the strain of Streptomyces venezuelae subsp. xanthophaeus Tu 2115. It is a quinone antibiotic. It has strong anti-bacterial activity on Halobacteria, and also has effects on gram-positive bacteria and mycoplasma.

It is produced by the strain of Fusarium sp. FE-71-1. It's an antibiotic produced by Marine microbes. Halymecin A had only weak antibacterial and fungal activity.

It is produced by the strain of Trichoderma harzianum SY-307. It has the activity against Pasteurella Piscicida SP.6395.

It is produced by the strain of Trichoderma harzianum. It has weak anti-gram-positive bacterial activity and anti-tumor effect, it can inhibit lymphoblastic leukemia L1210 and leukemia P388 with IC50 of 0.26 μg/mL. It inhibits the binding of viral particle regulatory (REV) proteins to [33P] labeled viral particle regulatory effector element (RRE) RNA, IC50 is 2.0 μmol/L. 200 μg/mL of Harziphilone does not protect CEM-SS cells from HIV-1 infection, and 38μmol/L of Harziphilone has cytotoxicity to mouse tumor cells M-109.

It is produced by the strain of Saccharopolyspora YL-0358M. It is an alkaloid antibiotic. It has weaker activity against gram-positive bacteria. It also shows cytotoxicity to lymphocytic leukemia L1210 and leukemia P388 cells.