Enzyme inhibitors

It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 33 μmol/L.

It is produced by the strain of Streptomyces sp. K99-5041. It can inhibit recombinant human lanosterol synthase (EC 5.4.99.7) with IC50 of 41 μmol/L.

It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL).

It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.11 μg/mL. The IC50 of reference Leucomentin-2 is 0.06 μg/mL.

It is produced by the strain of Paxillus panuoides. It is a free radical scavenger. It has strong inhibitory effect of lipid peroxidation with IC50 of 0.06 μg/mL. The IC50 of reference Leucomentin-4 is 0.11 μg/mL.

It is produced by the strain of Str. WK-4028. In the presence of 10-7 mol/L testosterone, it can significantly inhibit the growth of SC115 cells (IC50 is 0.6 μg/mL). It has no inhibitory effect on testosterone 5α-reductase, and it has no anti-gram-positive bacteria, gram-negative bacteria, fungi and yeast effects.

It is produced by the strain of Fusarium sp. RK-97-94. It is a P53-transfected tumor cell cycle inhibitor. It inhibits the cell cycle progression of H1299/TSP53 in G1 phase.

It is produced by the strain of Streptomyces sp. Mer-VD1207. It has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL), Luminacin D has the strongest activity.

It is produced by the strain of Streptomyces sp. Mer-VD1207. It has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL), Luminacin D has the strongest activity.

It is produced by the strain of Streptomyces sp. Mer-VD1207. It has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL), Luminacin D has the strongest activity.

It is produced by the strain of Streptomyces sp. Mer-VD1207. It has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL), Luminacin D has the strongest activity.

It is produced by the strain of Streptomyces sp. Mer-VD1207. It has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL), Luminacin D has the strongest activity.

It is produced by the strain of Str. sp. K Y 11783. It's an immunosuppressant. It has inhibitory effects on lymphocyte kinase (IC50 is 0.05 μmol/L), and it also inhibits mixed lymphocyte response (IC50 is 0.009 μmol/L). 83 μg/mL of Lymphostin has no effect on the gram-positive bacteria and negative bacteria.

It is produced by the strain of Periconia byssoides OUPS-N133. It is a cell adhesion inhibitor. It inhibits the adhesion of HL-60 cells to HU-VEC cells with IC50 of 5.6 μmol/L.

It is produced by the strain of Str. sp. K93-0711. It is an interleukin-6 inhibitor. It inhibits IL-6-dependent MH-60 cells and has no inhibitory effect on IL-6-independent MH-60 cells. In the presence of 0.1 U/mL IL-6, it inhibits IL-6-dependent MH-60 cells with IC50 of 30 μmol/L. It has no antimicrobial effect.

It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 0.3 and 1.2, respectively. It has anti-gram-positive bacteria effect.

It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.43 and 1.2, respectively. It has anti-gram-positive bacteria effect.

It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 3.64 and 28, respectively.

It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 19.3 and 59, respectively.

It is produced by the strain of Actinomadura atramentaria. It's a Type V collagenase inhibitor. It can inhibit type IV collagenase and type I collagenase with ID50 (μmol/L) of 1.82 and 5.1, respectively.