Bioactive by-products

It is a minor analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin.

It is the major analogue of a potent antitumour complex isolated from kibdelosporangium sp. MST-108465. It is structurally related to lysolipin and albofungin.

It is produced by the strain of Streptomyces. It is a potent nematocide and insecticide belonging to the bafilomycin class. It also has anti-fungal properties.

It is a chromone isolated from the filamentous fungus, lachnum sp. It possesses weak activity against bacteria but has not been extensively investigated.

It is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. It shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.

Mutilin, is used to perform biological studies with focus on antimicrobial activity. It is a minor metabolite of the pleuromutilin family isolated from pleurotus mutilus.

It is the dehydrated analogue of ophiobolin A and a major member of the ophiobolin complex of phytotoxic metabolites produced by many species of the genus bipolaris. It possesses a broad biological profile with antibacterial, antifungal, antitumour, herbicidal and nematocidal activities.

It is the major component of a family of cyclic lipopeptides produced by pseudomonas fluorescens pf-5. It is a moderate antifungal agent. It has a profound effect on the swarming motility of bacteria on agar surfaces.

It is a minor metabolite from the oligomycin complex produced by several species of streptomyces. It exhibits weak antibacterial activity and is considerably weaker as an antifungal agent.

It is an unusual sesquiterpene metabolite isolated from aspergillus terreus. It exhibits antitumor activity.

It is a broad spectrum antifungal metabolite isolated from several species of fusarium. It exhibits low animal-toxicity as evidenced by a lack of toxicity against artemia salina. It is a useful candidate for control of postharvest crop diseases.

A novel antibacterial analogue of the sulfonamide antibiotic, Sulfamethoxazole.

An antimicrobial peptide (AMP) isolated from a marine strain of bacillus subtilis. It is a linear lipopeptide composed of 7 peptides. It has shown initial bioactivity against pathogenic fungi, gram-positive and gram-negative bacteria, and cancer cell lines.

It is a thiourea derivative synthesized from 1,3-thiazole. It has activity against HIV-1 and CVB-5 virus.

DMAPT, an analogue of parthenolide, has been found to be effective in restraining the proliferation and metastasis of sorts of tumor cells through targeting NF-κB. DMAPT has been reported as an antiviral, anti-HIV and anti-Hepatitis C virus agent.

Aflavarin is a metabolite of the Sclerotia of Aspergillus flavus displaying anti-insectan activity against the fungivorous beetle Carpopbilus bemipterus.

Phomaligol A is an antibacterial metabolite produced from marine-derived fungus Aspergillus flavus.

Vibralactone B is an antibacterial compound produced from liquid fermentations of Stereum hirsutum that inhibits the growth of E. coli and Pseudomonas aeruginosa.

Cyclo(D-Leu-L-Pro) is a cyclodipeptide found in Phellinus igniarius. It exhibits antitumor and antifungal effects.

Asperlactone is a biologically active polyketide metabolite produced mainly from Aspergillus westerdijkiae. Asperlactone is a nematicidal, an insecticidal, an antibacterial and an antifungal agent.