Enzyme inhibitors

Fiscalin C is a substance P inhibitor produced by Neosartorya fischeri.

Fistupyrone is a substance produced by Streptornyces sp. TP-A0569. Inhibits the infection of cabbage with Alternaria brassicae.

Herquline B, a new platelet aggregation inhibitor produced by Penicillium herquei Fg-372.

Hibarimicin A is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.

Hibarimicin B is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.

Hibarimicin C is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.

Hibarimicin D is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria. It selectively inhibits the activity of src tyrosine kinase without affecting protein kinase A and C. It also has moderate anti-Gram-positive bacteria activity with a MIC of 0.8-12.56 μg/mL.

Hibarimicin E is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria.

Hibarimicin G is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria.

Hibarimicin H is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria.

Hibarimicinone is a tyrosine kinase inhibitor produced by Microbispora rosea subsp. hibaria.

Hispidospermidin is a phospholipase C inhibitor produced by Chaetosphaeronema hispidulum.

Histargin is an enzyme inhibitor produced by Streptomyces roseoviridis MF118-A5. It can inhibit carboxypeptidase B activity.

Hydroxyakalone is an inhibitor of Xanthosine oxidase (XOD, EC 1.2.3.2) produced by Agrobacterium aurantiacumn N81106. It inhibits XOD with an IC50 of 4.6 μmol/L, which is stronger than acathone (IC50 16.9 μmol/L).

5-Hydroxy-3,4,7-triphenyl-2,6-benzofurandione is a xanthine oxidase (XO) inhibitor produced by Peniophora sanguinea.

It is produced by the strain of Streptomyces sp. MQ22. It has the inhibitory effect of dexamethasone-glucocorticoid receptor. IC50 is 1.0 X 10-5 mol/L (rat liver cytosol). It has the anti-tumor cell activity, inhibits rat leukemia cell L1210 with IC50 of 0.12 μg/mL.

It is produced by the strain of Sreptomyces roseosporus M1696-AF3. It is a low molecular immune modulator.

It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research.

It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research.

It is produced by the strain of Streptomyces diastatochromogenes. It has antifungal, antiviral, immunosuppressive, cytotoxic and other activities, and is a specific inhibitor of V-type ATPase, which is an important tool for biochemical research.